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Afr1p Expression During Mitosis is Dependent on Mpk1p in Saccharomyces cerevisiae
Authors:Mingyong Xiong  Faiza Amin  Xuelei Tian  Limin Cao
Affiliation:1. College of Life Science, Capital Normal University, 105 Xisanhuanbeilu, Haidian District, Beijing, 100048, China
2. Department of Chemical Engineering and Materials Science, University of Minnesota, Twin Cities, Minneapolis, MN, USA
3. Department of Chemistry & Biochemistry, University of Agriculture Faisalabad, Faisalabad, Pakistan
Abstract:Afr1p induced by the mating pheromone confers α-factor resistance and leads to elongated bud during mitosis. In the present investigation Afr1p was expressed during mitosis and its expression amount was achieved to the level induced by α-factor. Additionally, Afr1p expression during mitosis was completely dependent on Mpk1p. The α-factor resistance was also dependent on the specific elements in the promoter of Afr1p. These results suggested that Afr1p may have important functions during mitosis.
Keywords:
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