高血压与老年人轻度认知功能障碍关系的研究现状

多年来的研究显示,高血压对老年人的认知功能有一定影响。高血压患者收缩压及其负荷值的增高可通过多种途径影响认知功能,脉压及脉压指数的增大可能是高血压患者认知损害的危险因素之一。高血压、脑动脉粥样硬化等使脑结构和功能改变、长期脑血流量降低,可导致认知功能损害。合理的降压治疗对预防认知功能障碍有一定效果。对高压与老年人轻度认知功能障碍的关系作一综述。

The Current Researches of the Hypertension and Mild Cognitive Dysfunction in the Elderly

The recent studies showed that the hypertension had a certain influence on cognition in the elderly. This paper describes the influence of hypertension on cognition in elderly. Pulse pressure is an important risk factor for hypertension, which can cause target organs of patients with hypertension damage. The greater of pulse pressure, the higher the incidence of target organ damage. The long-term cerebral blood flow reduction can lead to cognitive impairment. Elevated serum cholesterol is an important risk factor for mild cognitive impairment in middle age. The repeated episodes of low blood pressure and low blood sugar maybe caused by impropriate treatment of lowering blood pressure and lowering blood glucose, which results in insufficient blood supply to the brain and the brain cells hypoxic-isehemic injury, ultimately lead to cognitive impairment. The reasonable treatment of lowering blood pressure has a certain effect on the prevention of cognitive impairment.