双氯芬酸钾用于预防放置宫内节育器疼痛的临床研究

目的:观察双氯芬酸钾用于预防放置宫内节育器(IUD)所致疼痛的效果。方法:随机选取经剖宫产分娩后和阴道分娩后的两组妇女各100例,两组分别放置宫铜200IUD和TCu380IUD:剖宫产分娩后放置宫铜200IUD的妇女49例(观察组24例,对照组25例),放置TCu380IUD的妇女51例(观察组26例,对照组25例)。阴道分娩后放置宫铜200IUD的妇女50例(观察组和对照组各25例),放置TCu380IUD的妇女50例(观察组和对照组各25例)。观察双氯芬酸钾在置器术中、术后30min、术后6h、术后当晚睡前及术后第3日晚睡前预防疼痛的效果及服药的副反应等。结果:阴道分娩后置器的妇女,观察组和对照组在术中、术后30min、术后6h、术后当晚睡前及术后第3日晚睡前的疼痛分级差异均无统计学意义(P>0.05)。剖宫产分娩后放置宫铜200IUD的妇女,观察组和对照组比较,在术中及术后第3日晚睡前疼痛分级差异有统计学意义(P<0.05);放置TCu380IUD的妇女,观察组和对照组术后30min的疼痛分级差异有统计学意义(P<0.05)。结论:双氯芬酸钾用于预防剖宫产分娩后放置IUD所致疼痛有一定的效果,但未发现其能预防阴道分娩后放置IUD所致的疼痛。

Effect of diclofenac potassiumon on pain relief among women with intrauterine device insertion

Objective：To explore the effect of diclofenac potassium on pain relief among women with intrauterine device（IUD） insertion.Methods：One hundred women who had experienced cesarean section or vaginal delivery were randomly selected.VCu200 IUD insertion was conducted in 49 women who had experienced cesarean section（24 for the treatment group and 25 for the control group） and 50 women who had experienced vaginal delivery（25 for the treatment group and 25 for the control group）.TCu380 IUD insertion was conducted in 51 women who had experienced cesarean section（26 for the treatment group and 25 for the control group） and 50 women who had experienced vaginal delivery（25 for the treatment group and 25 for the control group）.The effects of diclofenac potassium on pain relief during the insertion,at 30 min and 6 hours after the insertion,and at the night and the third night following the procedure were evaluated.Results：Among women experiencing vaginal delivery,there were no significant differences in pain scores during the insertion,at 30 min and 6 hours after the insertion,and at the night and the third night following the procedure between the treatment and control groups（P〈0.05）.Among women experiencing cesarean section with VCu200 IUD insertion,there were significant differences in pain scores during the insertion and at the third night following the procedure between the treatment and control groups（P〈0.05）,while there was significant difference at 30 min after the insertion among those with TCu380 IUD insertion（P〈0.05）.Conclusion：Diclofenac potassium has some effect on IUD insertion-related pain relief among women who had experienced cesarean section,while had no effect for women who had experienced vaginal delivery.