缺血性二尖瓣反流的机制、诊断和治疗研究进展

缺血性二尖瓣反流是心肌梗死所致心室结构及功能的改变引起二尖瓣关闭不全,是冠心病常见的并发症。左室重构基础上发生的瓣叶栓拉与关闭动力失衡,瓣环形变等多种因素参与缺血性二尖瓣反流的发生。心脏超声不仅可评估二尖瓣反流严重程度,还能明确瓣叶、瓣环、腱索、乳头肌和左室壁结构功能改变,有助于确诊和指导治疗。

Advances in Mechanism, Diagnosis and Therapy of Ischemic Mitral Regurgitation

Ischemic mitral regurgitation, the mitral insufficiency caused by structural and functional disorders of the left ventricle after myocardial infarction, is a common complication of coronary artery disease. Leaflet tethering and tenting, annular deformation and other mechanisms jointly contribute to ischemic mitral regurgitation. Echocardiography allows not only the estimation of the severity of mitral regurgitation, but also the structural and functional changes of leaflets, annulus, chordae tendineae and papillary muscle. Thus, echocardiography was the method of choice in diagnosis and follow-up of ischemic mitral regurgitation.