| 云南白药对比格犬牙龈炎的治疗作用 |
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| 引用本文： | 姚尧,杨安民,张光毅,彭海燕,杜俊蓉. 云南白药对比格犬牙龈炎的治疗作用[J]. 实用口腔医学杂志, 2007, 23(4): 531-533 |
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| 作者姓名： | 姚尧 杨安民 张光毅 彭海燕 杜俊蓉 |
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| 作者单位： | 1. 成都四川大学华西药学院药理学与生物制药学系,610041
2. 成都市安民口腔诊所 |
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| 摘 要： | 目的:评价云南白药对比格犬牙龈炎的治疗作用。方法:12只符合条件的比格犬随机分为云南白药组和空白对照组。2组动物分别用浸有1.23g/L云南白药溶液或生理盐水的棉球敷于牙龈治疗,1min/次,2次/d,持续14d。在给药前和末次给药后24h分别盲法对动物的菌斑(P),牙龈炎症状(G)和炎性浸润(INF)评分。结果:空白对照组动物的P、G、INF没有显著性差异(P>0.1),云南白药组动物的各评分指标均有显著性改善(P<0.05)。结论:云南白药可抑制比格犬牙龈炎菌斑形成,减轻牙龈炎症状和炎细胞的聚集。实验结果提示云南白药可能对临床牙龈炎有一定治疗作用。
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| 关 键 词： | 云南白药 牙龈炎 菌斑 炎性浸润 牙周病 |
| 文章编号： | 1001-3733（2007）-04-0531-03 |
| 修稿时间： | 2006-10-08 |
Therapeutic effects of Yunnan Baiyao on gingivitis in beagle dogs |
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| Yao Yao, Yang Anmin, Zhang Guangyi,et al.. Therapeutic effects of Yunnan Baiyao on gingivitis in beagle dogs[J]. Journal of Practical Stomatology, 2007, 23(4): 531-533 |
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| Authors: | Yao Yao Yang Anmin Zhang Guangyi et al. |
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| Affiliation: | Yao Yao, Yang Anmin, Zhang Guangyi, et al. Department of Pharmacology, West China College of Pharmacy, Sichuan University, Chengdu 610041, China |
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| Abstract: | Objective:To test the effects of Yunnan Baiyao on beagle dogs with gingivitis. Methods: 12 chosen beagle dogs were randomly distributed into two groups: control group and Yunnan Baiyao group. Normal saline (control group) or 1.23 g/L Yunnan Baiyao solution was applied on the dogs' teeth twice daily for 14 days. At day 0 and day 15, the scores for plaque (P), gingivitis (G) and inflammatory infiltrate (INF) were evaluated blindly. Results: P, G, and INF did not show any alteration in control group (P>0.1), while in Yunnan Baiyao group, there were significant reductions in all scores (P<0.05). Conclusion: Yunnan Baiyao inhibited plaque formation, abated existing gingivitis and inflammatory cells aggregation in beagle dogs. The present results suggested that Yunnan Baiyao may be a good option for the treatment of gingivitis. |
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| Keywords: | Yunnan Baiyao Gingivitis Plaque Inflammatory cell infiltration Periodontal disease |
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