| 大鼠中脑导水管周围灰质和中缝核簇内P物质受体定位分布的免疫细胞化学研究 |
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| 引用本文： | 王智明,李云庆,施际武.大鼠中脑导水管周围灰质和中缝核簇内P物质受体定位分布的免疫细胞化学研究[J].中国神经科学杂志,1996(1). |
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| 作者姓名： | 王智明 李云庆 施际武 |
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| 作者单位： | 西安第四军医大学基础部，西安第四军医大学解剖学教研室，西安第四军医大学梁琚脑研究中心 |
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| 摘 要： | 本研究用免疫细胞化学染色技术对大鼠中脑导水管周围灰质（ＰＡＧ）和中缝核簇内Ｐ物质受体的精确定位分布进行了系统地观察。Ｐ物质受体阳性的神经元胞体和纤维主要密集地分布于ＰＡＧ吻段的背侧部、中段的外侧部和尾段的腹侧部。在线形核、中缝背核、中缝正中核、中缝桥核、中缝大核和中缝隐核可见中等密度至高密度的阳性神经元胞体和纤维；在中央下核和中缝苍白核内仅见少量阳性纤维。
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| 关 键 词： | P物质受体 中脑导水管周围灰质 中缝核簇 免疫细胞化学 大鼠 |
IMMUNOCYTOCHEMICAL LOCALIZATION OF SUBSTANCE P RECEPTOR IN THE MIDBRAIN PERIAQUEDUCTAL GRAY AND RAPHE NUCLEI OF THE RAT |
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| WANG Zhi-Ming, LI Yun-Qing, SHI Ji-Wu.IMMUNOCYTOCHEMICAL LOCALIZATION OF SUBSTANCE P RECEPTOR IN THE MIDBRAIN PERIAQUEDUCTAL GRAY AND RAPHE NUCLEI OF THE RAT[J].Neuroscience Bulletin,1996(1). |
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| Authors: | WANG Zhi-Ming LI Yun-Qing SHI Ji-Wu |
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| Abstract: | The immunocytochemical staining technique was used in the present study to investigate the precise localization of the substance P receptor (SPR) in the rat midbrain periaqueductal gray (PAG) and raphe nuclei. Dense SPR-like immunoreactive (SPR-LI) neuronal cell bodies and fibers mainly distributed in the dorsal subdivision, lateral subdivision or ventral subdivision at the rostral, middle or caudal level of the PAG. Dense to moderate density of SPR-LI neuronal cell bodies and fibers were localized in the nucleus linearis, nucleus raphe dorsalis, nucleus raphe median, nucleus raphe pontis, nucleus raphe magnus and nucleus raphe ohscurus. Sparse SPR-LI fibers were occasionally seen in the nucleus centralis inferior and nucleus raphe pallidus. |
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| Keywords: | Substance P receptor Midbrain periaqueductal gray Raphe nuclei Immunocytochemistry Rat |
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