| 48家医院自身抗体检测的质控总结 |
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| 引用本文： | 邓学新,唐福林.48家医院自身抗体检测的质控总结[J].中华风湿病学杂志,2004,8(7):387-390. |
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| 作者姓名： | 邓学新 唐福林 |
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| 作者单位： | 100730,中国医学科学院,中国协和医科大学,北京协和医院风湿免疫科 |
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| 摘 要： | 目的了解我国自身抗体的检测现状，提高现有的检测水平。方法通过发函的方式确定48家医院为参与单位，质控项目包括抗核抗体、抗dsDNA抗体、抗可提取性核抗原(ENA)抗体、抗线粒体抗体和抗平滑肌抗体。标本发放和结果分析采用双盲操作，质控标本共计11份。结果抗核抗体、抗dsDNA抗体、抗ENA抗体、抗线粒体抗体和抗平滑肌抗体正确率分别是47％、70％、46％、95％和40％。结论总体情况不容乐观，试剂盒质量参差不齐，检测人员水平不一，应从选择好的方法和提高认识水平方面着手改善国内现状。
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| 关 键 词： | 医院 自身抗体 检测 质量控制 实验室诊断 |
| 修稿时间： | 2004年2月11日 |
Quality control of autoantibodies detection with analysis |
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| DENG Xue-xin,TANG Fu-lin. Chinese Rhe-umatology Association.Quality control of autoantibodies detection with analysis[J].Chinese Journal of Rheumatology,2004,8(7):387-390. |
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| Authors: | DENG Xue-xin TANG Fu-lin Chinese Rhe-umatology Association |
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| Institution: | DENG Xue-xin,TANG Fu-lin. Chinese Rhe-umatology Association,Department of Rheumatology,Peking Union Medical College Hospital,Beijing 100730,China |
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| Abstract: | Objective To make an investigation for autoantibodies detection in China. Method Forty-eight hospitals were included by mail or Email. The items of QC include ANA, anti-ENA antibody, anti-dsDNA antibody, anti-mitochondria antibody and anti-smooth muscle antibody. The distribution of samples and analysis of the testing results was double-blinded. Result The correct rate of ANA, anti-ENA antibody, anti-dsDNA antibody, anti-mitochondria antibody and anti-smooth muscle antibody were 47%, 70%, 46%, 95%and 40% respectively. Conclusion The overall results are not optimistic. The quality of detecting kits is not all good, neither level of technicians. This condition should be changed by selecting better methods and improving understanding. |
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| Keywords: | Antibodies Quality control Analysis |
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