氢清除法局部血流仪研制及氢清除曲线微机自动分析

应用新型电子器件及单片计算机,研制出一种高性能的氢清除法局部血流量测定仪;并设计了相应的计算机处理程序,自动采集氢清除曲线,用最小二乘法拟合曲线,根据拟合曲线计算出局部血流量。用该系统测定了大鼠纹状体脑血流量,拟合曲线与氢清除曲线基本上完全重合,拟合参数正确无误。血流仪设计合理,工作稳定、可靠。用微机自动对氢清除曲线进行数据采集、分析,提高了测量结果的准确性,并可及时得出实验结果。

The Design of an Instrument Furnished with Hydrogen Clearance Technique for Measuring Local Blood-flow and the Microcomputer Analysis Curve on Hydrogen Clearance

A new instrument,furnished with hydrogen clearance technique for measuring local blood-flow,was designed by use of new electronic components and a microcontroller.The corresponding program was developed.The curve of hydrogen clearance was sampled automatically by microcomputer,fitted into an exponential function by least square method,and then the local blood-flow was calculated.The cerebral blood-flow in the rat's striatum had been measured using the system.The fitted curve corresponds with the curve of hydrogen clearance and the obtained parameter was correct.The design of the instrument was reasonable.It can work reliably and stably.The calculated results are more accurate and they can be acquired more quickly,because the curve of hydrogen clearance is automatically sampled and analyzed by the microcomputer.