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Experimental Study on the Antibacterial Effect of Origanum Volatile Oil on Dysentery Bacilli In Vivo and In Vitro
引用本文:廖芳,黄庆华,扬振德,许汉林,高清华. Experimental Study on the Antibacterial Effect of Origanum Volatile Oil on Dysentery Bacilli In Vivo and In Vitro[J]. 华中科技大学学报(医学英德文版), 2004, 24(4): 400-403. DOI: 10.1007/BF02861878
作者姓名:廖芳  黄庆华  扬振德  许汉林  高清华
作者单位:[1]DepartmentofMicrobiology,TongjiMedicalCollege,HuazhongUniversityofScienceandTechnology,Wuhan430030,China [2]DepartmentofMicrobiology,HubeiCollegeofTraditionalChineseMedicine,Wuhan430060,China
摘    要:To observe the germistatic and germicidal effects of origanum volatile oil (OVI) on the dysentery bacteria, the abdominal cavity of mice was infected with Shigella sonne (Sh. sonnei) and Shigella flexneri (Sh. flexneri) F2a. After OVI was given to the mice via gastric lavage, the effects of OVI on the infected mice were observed. The minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) for dysentery bacteria were determined in vitro. The resuits showed that origanum volatile oil showed obvious protective effect on mice infected with Sh. sonnei and Sh. flexneri F2a. and it had germistatic and germicidal effects on dysentry bacteria. We are led to conclude that origanum volatile oil is an effective medicine against the infection of dysentery bacteria.

关 键 词:实验研究 抗菌作用 牛至属植物 挥发性油 痢疾杆菌 体内 试管内 内科学 杆菌性痢疾
收稿时间:2003-06-30

Experimental study on the antibacterial effect of origanum volatile oil on dysentery bacilliin vivo andin vitro
Liao Fang,Huang Qinghua,Yang Zhende,Xu Hanlin,Gao Qinhua. Experimental study on the antibacterial effect of origanum volatile oil on dysentery bacilliin vivo andin vitro[J]. Journal of Huazhong University of Science and Technology. Medical sciences, 2004, 24(4): 400-403. DOI: 10.1007/BF02861878
Authors:Liao Fang  Huang Qinghua  Yang Zhende  Xu Hanlin  Gao Qinhua
Affiliation:1. Department of Microbiology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
2. Department of Microbiology, Hubei College of Traditional Chinese Medicine, Wuhan 430060, China
Abstract:Summary To observe the germistatic and germicidal effects of origanum volatile oil (OVI) on the dysentery bacteria, the abdominal cavity of mice was infected withShigella sonne (Sh. sonnei) andShigella flexneri (Sh. flexneri) F2a. After OVI was given to the mice via gastric lavage, the effects of OVI on the infected mice were observed. The minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) for dysentery bacteria were determinedin vitro. The results showed that origanum volatile oil showed obvious protective effect on mice infected withSh. sonnei andSh. flexneri F2a. and it had germistatic and germicidal effects on dysentry bacteria. We are led to conclude that origanum volatile oil is an effective medicine against the infection of dysentery bacteria. LIAO Fang, female, born in 1960, Associate Professor
Keywords:origanum volatile oil  antibacterial effect  dysentery bacilli
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