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抗甲状腺药物诱导的抗中性粒细胞胞质抗体相关性小血管炎
引用本文:李欣.抗甲状腺药物诱导的抗中性粒细胞胞质抗体相关性小血管炎[J].肾脏病与透析肾移植杂志,2011,20(1):67-71.
作者姓名:李欣
作者单位:上海交通大学附属瑞金医院肾脏内科,上海,200025
摘    要:以丙基硫氧嘧啶(Propylthiouracil,PTU)、他巴唑(Thiamazole,MMI)等为代表的抗甲状腺药物(Antithyroid drugs,ATD)广泛应用于临床甲状腺功能亢进的治疗,同时也是导致药物相关性血管炎最常见的原因之一,其临床特点与原发性小血管炎相比有其特殊之处。本文回顾性分析国内外相关文献,对本病临床特点加以综述,总结其诊治进展,以期指导临床。

关 键 词:药物相关性血管炎  抗甲状腺药物  丙基硫氧嘧啶  他巴唑

Anti-thyroid drugs induced antieutrophil cytoplasmic antibody (ANCA) associated vasculitis
LI Xin.Anti-thyroid drugs induced antieutrophil cytoplasmic antibody (ANCA) associated vasculitis[J].Chinese Journal of Nephrology, Dialysis & Transplantation,2011,20(1):67-71.
Authors:LI Xin
Institution:LI Xin,CHEN Nan Department of Nephrology,Ruijin Hospital,Shanghai Jiaotong University School of Medicine,Shanghai 200025,China
Abstract:Anti-thyroid drugs are widely used in patients as treatment for hyperthyroidism,especially the drugs of propylthiouracil(PTU)and thiamazole(MMI).These are also one of the most common causes of drug-induced vasculitis.Differences of clinical features,diagnosis and treatment between vasculitis induced by ATD and primary AAV still need to be fully investigated.Literatures are collected and studied in this review.
Keywords:drug-induced vasculitis Anti-thyroid drugs Propylthiouracil Thiamazole  
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