| 高尿酸血症对血清一氧化氮及内皮素-1水平的影响 |
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| 引用本文： | 周传堃,鲁跃华,葛正庆.高尿酸血症对血清一氧化氮及内皮素-1水平的影响[J].现代临床医学,2011,37(6):427-427. |
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| 作者姓名： | 周传堃 鲁跃华 葛正庆 |
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| 作者单位： | 成都大学附属医院,四川成都,610081 |
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| 摘 要： | 目的:观察高尿酸血症对血清一氧化氮(NO)及内皮素-1(ET-1)水平的影响.方法:检测92例观察对象血尿酸水平,分为高血尿酸组( HUA)45例与正常血尿酸组(NUA)47例,分别检测2组每一个体的血清NO及ET -1水平进行比较分析.结果:HUA组NO水平低于NUA组(P＜0.01)；HUA组ET -1水平高于NU...
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| 关 键 词： | 高尿酸血症 一氧化氮 内皮素-1 血管内皮功能 |
Effect of Hyperuricemia to NO and ET-1 Serum Level |
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| ZHOU Chuan-kun,LU Yue-hua and GE Zheng-qing.Effect of Hyperuricemia to NO and ET-1 Serum Level[J].Journal of Modern Clinical Medicine,2011,37(6):427-427. |
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| Authors: | ZHOU Chuan-kun LU Yue-hua and GE Zheng-qing |
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| Institution: | ZHOU Chuan-kun,LU Yue-hua,GE Zheng-qing(Affiliated Hospital of Chengdu University,Sichuan Chengdu 610081,China) |
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| Abstract: | Objective:To evaluate the effect of hyperuricemia to NO and ET-1 serum level.Methods:NO and ET-1 serum level was measured in 45 patients with hyperuicemia(HUA) and 47 normal uric acid subjects(NUA).Results:NO level in HUA was siguificautly lower than that in NUA(P<0.01),ET-1 level in HUA was siguificautly higher than that in NUA(P<0.01).Conclusion:hyperuricemia is a risk factor of endothelial dysfunction,and it is correlated with hypertension and athrosclerosis. |
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| Keywords: | hyperuricemia NO ET-1 endothelial function |
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