| 伊立替康联合氟尿嘧啶二线治疗晚期结直肠癌观察 |
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| 引用本文： | 王晓毓,白娟,郑玲,伍健蓉.伊立替康联合氟尿嘧啶二线治疗晚期结直肠癌观察[J].现代临床医学,2011,37(5):352-353. |
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| 作者姓名： | 王晓毓 白娟 郑玲 伍健蓉 |
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| 作者单位： | 成都大学附属医院,四川,成都,610081 |
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| 摘 要： | 目的:观察伊立替康(CPT-11)联合氟尿嘧啶治疗一线化疗失败的晚期结直肠癌的疗效.方法:61例晚期结直肠癌患者,均为经奥沙利铂、氟尿嘧啶、亚叶酸钙等药物一线化疗失败者,行伊立替康联合氟尿嘧啶方案治疗,第1天伊立替康180 mg/m2静脉滴注90 min,第1天、第2天亚叶酸钙200 mg/m2静脉滴注,第1天、第2天...
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| 关 键 词： | 伊立替康 氟尿嘧啶 结直肠癌 化疗 |
Clinical Trials of Treating Advanced Colorectal Cancer with Irinotecan Plus 5-Fu |
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| WANG Xiao-yu,BAI Juan,ZHENG Ling and WU Jian-rong.Clinical Trials of Treating Advanced Colorectal Cancer with Irinotecan Plus 5-Fu[J].Journal of Modern Clinical Medicine,2011,37(5):352-353. |
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| Authors: | WANG Xiao-yu BAI Juan ZHENG Ling and WU Jian-rong |
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| Institution: | WANG Xiao-yu,BAI Juan,ZHENG Ling,WU Jian-rong(Affiliated Hospital of Chengdu University,Sichuan Chengdu 610081,China) |
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| Abstract: | Objective:To observe the efficacy of irinotecan(CPT-11) plus 5-Fu after first-line chemotherapy failure in patients with advanced colorectal cancer.Methods:61 patients with advanced colorectal cancer whose disease had progressed after treatment with first-line oxaliplatin and 5-Fu/LV chemotherapeutics were treated with irinotecan(CPT-11) plus 5-Fu:CPT-11 180 mg /m2 d1,dripping into vein in 90 minutes;LV 200 mg/m2 d1-d2,dripping into vein;5-Fu 400 mg/m2 d1-d2 and 600 mg/m2 d1-d2 continue dripping into vein i... |
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| Keywords: | Irinotecan 5-Fu colorectal cancer chemotherapy |
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