| 银杏外种皮多糖对不同状态小鼠血清SOD和MDA形成的影响 |
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| 引用本文： | 许爱华,陈华圣,王玲,王茜.银杏外种皮多糖对不同状态小鼠血清SOD和MDA形成的影响[J].中国中药杂志,1998,23(12):746-747. |
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| 作者姓名： | 许爱华 陈华圣 王玲 王茜 |
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| 作者单位： | 扬州大学医学院 扬州 225002 |
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| 基金项目： | 江苏省教委自然科学基金 |
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| 摘 要： | 目的:观察银杏外种皮多糖(GBEP)对不同状态小鼠血清SOD和MDA形成的影响。方法:用GBEP给荷瘤小鼠、环磷酰胺(CTX)抑制小鼠及正常小鼠灌胃给药,检测小鼠血清中的SOD活性及MDA含量。结果:GBEP可明显提高荷瘤小鼠血清SOD活性,并能降低其MDA含量,也能改善CTX抑制小鼠的上述指标,但对正常小鼠则无明显影响。结论:GBEP可促进机体在病理状态下的自由基清除能力。
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| 关 键 词： | 银杏 多糖 SOD MDA 自由基 |
| 收稿时间： | 1997/6/12 0:00:00 |
Influence of Ginkgo biloba L. Exocarp Polysaccharides on Serum Superoxide Dismutase Activity and Malondialdehyde Level in Mice Under Different States |
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| Xu Aihua;Chen Huasheng;Wang Ling; Wang Qian.Influence of Ginkgo biloba L. Exocarp Polysaccharides on Serum Superoxide Dismutase Activity and Malondialdehyde Level in Mice Under Different States[J].China Journal of Chinese Materia Medica,1998,23(12):746-747. |
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| Authors: | Xu Aihua;Chen Huasheng;Wang Ling; Wang Qian |
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| Institution: | Medical College of Yangzhou University, Yangzhou 225002. |
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| Abstract: | Objective:To study the influence of Ginkgo biloba exocarp polysaccharides(GBEP) on serum superoxide dismutase(SOD) activity and malondialdehyde(MDA) level in mice under different states.Method:GBEP was orally administrated to S 180 bearing mice,cyclophosphamide(CTX) intoxicated mice and normal mice.The contents of SOD and MDA in the mice's blood were checked.Result:GBEP significantly enhanced SOD activity and decreased MDA content in S 180 bearing mice.Similar effects were observed in CTX intoxicated mice.In normal mice,however, no such effects were observed.Conclusion:GBEP may modulate the free radical system in mice under abnormal states. |
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| Keywords: | Ginkgo biloba polysaccharide SOD MDA free radical |
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