生物反馈治疗便秘型肠易激综合征的临床疗效研究

目的探讨生物反馈治疗便秘型肠易激综合征（IBS-C）患者的临床效果。方法对30例IBS-C患者给予生物反馈治疗，每疗程5次，应用症状评分、焦虑自评量表（SAS）、抑郁自评量表（SDS）及简明健康调查量表（sF-36）分别评估患者生物反馈治疗前后的临床症状、精神状态及生活质量的变化。结果生物反馈治疗后，患者肠道总体症状，腹痛／腹部不适、腹胀、排便形状异常、排便过程异常的症状积分均较治疗前有显著降低（12．31±2．01）分vs（19．16±2．17）分、（2．95_＋0．57）分vs（5．04±1．04）分、（2．64±0．92）分vs（4．25±1．09）分、（3．66±1．09）分VS（5．10±0．57）分、（3．06±1．08）分vs（4．77±0．95）分，均P〈0．01]，差异有统计学意义，其中以腹痛／腹部不适症状的改善最为明显。IBS—C患者的SAS积分、SDS积分也分别较治疗前明显下降（39．53±6．39）分VS（44．43±7．89）分，P〈0．05；（40．70＋8．38）分VS（46．46±8．74）分，均P〈0．05]。sF-36得分在生理职能、社会功能、精力、情感职能及精神健康5个维度积分较治疗前明显增加（74．16±21．25）分VS（57．0±39．40）分、（86．21±13．54）分VS（75．54±20．96）分、（75．16±13．42）分VS（64．66±20．54）分、（78．87±28．36）分V8（57．76±46．26）分、（81．60±16．08）分VS（71．20±22．04）分，均P〈0．05]。结论生物反馈治疗能够改善IBS-C患者临床症状，缓解焦虑和抑郁的情绪，提高生活质量。

Clinical efficacy of biofeedback therapy on constipation-predominant irritable bowel syndrome

Objective To investigate the clinical effects of biofeedback therapy on constipation-predomi- nant irritable bowel syndrome（ IBS-C ）. Methods 30 patients with IBS-C were given to biofeedback therapy, 5 times every treatment course .and then their clinical symptoms, mental state and quality of life before the treatment and at the end of treatment with biofeedback therapy were respectively evaluated by symptom scores, self-rating anxiety scale （SAS）, self-rating depression scale （SDS）, and short form 36 health survey questionnaire （SF-36）. Results Post-treatment with biofeedback therapy, there were very significant decrease in total and subscales scores of bowel symptom including abdominal pain/discomfort, abdominal distension, abnormal appearance of defe- cation ,abnormal process of defecation（ （ 12.31±2.01 ） vs （ 19.16±2.17）, （2.95±0.57） vs （ 5.04± 1.04）, （ 2.64± 0.92） vs （ 4.25± 1.09）, （ 3.66± 1.09） vs （ 5.10±0.57）, （ 3.06± 1.08） vs （ 4.77±0.95 ） respectively, P〈0.01 ）. The integration of SAS and SDS were obviously decreased after treatment（（39.53±6.39） vs （44.43±7.89）, P〈0.05; （40.70±8.38） vs （46.46±8.74）, P〈0.05 ）, the SF-36 scores were also improved in five dimensions including role- physieal,social-funetioning,vitality,role-emotional and mental health（（74.16±21.25） vs （57.0±39.40） ,（86.21± 13.54） vs （75.54±20.96）, （75.16±13.42） vs （64.66±20.54）, （78.87±28.36） vs （57.76±46.26）, （81.60± 16.08） vs （71.20±22.04） respectively, P〈 0. 05 ） . Conclusion Biofeedback therapy can improve the clinical symptoms, alleviate the moods of anxiety and depression, and improve the quality of life in patients with IBS-C.