慢性重症肝炎和肝硬化患者医院感染调查分析

目的：探讨慢性重症肝炎及肝硬化患者发生医院感染情况，为防治医院感染提供依据。方法：回顾性调查2007年度收住本院的慢性重症肝炎及肝硬化患者发生医院感染的情况。结果：医院感染率为13．7％，恶化或死亡的医院感染率（18．5％）高于好转或痊愈组（12．4％）（P〈0．05）。患者年龄越大，并发医院感染越多（P〈0．001）。院内感染以腹腔感染占首位，致病菌以真菌或条件致病菌为主；其易感因素为免疫抑制剂和广谱抗生素的使用、侵入性诊疗、糖尿病等；医院感染导致各种严重致死性的并发症增多（42／113）。结论：慢性重症肝炎及肝硬化患者易发生医院感染，院内感染会使病情恶化或死亡发生率增高，预后差。

Analysis on hospital infection of chronic hepatitis gravis and hepatic cirrhosis

Objective:To investigate the hospital infection of chronic hepatitis gravis and hepatic cirrhosis,and to provid possible ways to prevent and cure the infection.Methods:Patients with chronic hepatitis gravis and hepatic cirrhosis,treated in 2007,were retrospectively reviewed.Results:The rate of hospital infection was 13.7%.The rate of aggravation group(18.5%) was higher than that in restoration group(12.4%)(P<0.05).Patients who were older had more hospital infection(P<0.001).peritonitis was the first place i...