米非司酮与妈富隆治疗围绝经期功血的临床疗效比较研究

目的为了比较米非司酮与妈富隆治疗围绝经期功血的临床疗效。方法总结2010年10月至2012年11月期间在我院治疗的围绝经期功能失调性子宫出血患者40例资料,按照患者用药方法不同进行分组:单纯米非司酮治疗的患者20例为对照组,对照组基础上加用妈富隆片进行治疗的20例为观察组,术后统计疗效和控制出血时间,最后统计学方法比较组间差异性。结果观察组患者平均控制出血时间为(17.4±3.8)min,平均完全止血时间为(38.1±6.9)min,显著低于对照组平均时间(P<0.05),观察组患者总有效率95%,显著高于对照组(P<0.05)。结论米非司酮联合妈富隆治疗围绝经期功能失调性子宫出血具有满意的临床疗效。

Comparative Study on the Clinical Curative Effect of Mifepristone and Marvelon on Perimenopausal Uterine Bleeding

Objective To compare the clinical effect of mifepristone combined with Marvelon on perimenopausal uterine bleeding. Methods From 2010 October to 2012 year in November in our hospital during the treatment of perimenopausal dysfunctional uterine bleeding in patients with 40 cases, according to the patient different grouping methods： 20 patients with simple mifepristone treatment as control group, were treated with Marvelon tablet for treatment of 20 cases of the observation group, the statistical effect and control the bleeding time after operation, the final statistical methods were used to compare the difference between sex. Results The patients in the observation group average control bleeding time was （17.4±3.8）min, average hemostasis time was （38.1± 6.9）min, significantly lower than the control group mean time （P〈0.05）, patients in the observation group the total effective rate was 95%, significantly higher than that of the control group（P〈0.05）. Conclusion Mifepristone combined Marvelon on perimenopausal dysfunctional uterine bleeding clinical curative effect is satisfactory.