Choriocarcinoma of the lung: report of a case |
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Authors: | Takayuki Ibi Kyoji Hirai Ryuzo Bessho Masashi Kawamoto Kiyoshi Koizumi Kazuo Shimizu |
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Institution: | (1) Department of Cardiovascular and Thoracic Surgery, Nippon Medical School, Chiba Hokuso Hospital, 1715 Kamagari Inzai-shi, Chiba 270-1694, Japan;(2) Division of Diagnostic Pathology, Nippon Medical School Hospital, Tokyo, Japan;(3) Department of Surgery, Nippon Medical School Hospital, Tokyo, Japan |
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Abstract: | In this report, a 27-year-old woman with a solitary pulmonary nodule is described. Because computed tomography-guided biopsy
could not confirm the diagnosis, surgical treatment was performed by video-assisted thoracic surgery. Histological findings
showed cytotrophoblasts and syncytiotrophoblasts, suggesting choriocarcinoma. However, there were no abnormal findings on
gynecological examination, including ultrasonography, magnetic resonance imaging, and positron-emission tomography. Choriocarcinoma
is a malignant neoplasm and can arise after a pregnancy, as a component of germ cell tumors, or in association with a poorly
differentiated somatic carcinoma. Our patient, a young female with an antecedent gestation, has no recurrence after surgery.
There were tumor emboli in pulmonary arteries and no component of primary lung carcinoma on histological examination. These
findings indicate that the lesion was a metastasis of gestational choriocarcinoma. A rare case of a patient with metastatic
gestational choriocarcinoma of a solitary pulmonary nodule without any uterine abnormality is presented. |
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