南昌地区亚临床甲状腺功能减退症的筛查分析

目的　了解南昌地区亚临床甲状腺功能减退症 (SCH)的患病率。方法　于 1997年 12月～ 1998年 6月 ,对南昌地区的四县五区 2 110人 ,其中成人 14 4 2人 ,年龄为 (18～ 70岁 ) ;儿童 6 6 8人 ,年龄为 (3岁～ 6岁 11个月 ) ,进行甲状腺激素筛查测定。结果　 (1)南昌地区SCH总患病率 6 .1% ,其中成人患病率为 4 .6 % ,儿童患病率 9.1% ,儿童患病率高于成人 (P <0 .0 0 1) ;(2 )女性患病率为 7.4 % ;男性患病率为 4 .9% ,女性患病率高于男性 (P <0 .0 5 ) ;(3)SCH患病率与年龄结构比表明 :成人组 :6 0岁以上年龄组患病率最高 10 .4 % ,其次 5 0岁组 (5 .7% )和 18岁组 (5 .6 % ) ,但后两组比较差异无显著性 ,说明两个年龄段皆为患病高峰期。儿童组则以 3岁年龄组 ,患病率最高 (15 .9% ) ,其次是 6岁年龄组 (9.5 % ) ,两者自比或与成人组比较 ,差异皆有显著性 (P <0 .0 5 ) ;(4)SCH的患病率与甲状腺肿的发生无明显相关性。结论　南昌地区SCH的患病率较高 ,SCH的发生与性别和年龄相关

Screening analysis for subclinical hypothyroidism in Nanchang area

Objective To investigate the prevalence of subclinical hypothyroidism (SCH) in Nanchang area. Methods TSH, TT 3 and TT 4 levels in 2110 subjects were determined in Nanchang area including four counties and five districts. Results (1) The overall SCH prevalence in Nanchang area was 6.1%; being 9.1% in children, which was higher than that in adults (4.6%, P<0.001). (2) The SCH prevalence in women was 7.4%, higher than that in men (4.9%, P<0.05). (3) The relationship between the SCH prevalence and the age showed that the highest SCH prevalence in adults was in the 60 years old group (10.4%), followed by the 50 years old group (5.7%) and the 18 years old group (5.6%), but there was no difference between the latter two groups. In children, the highest SCH prevalence was 3 years old group (15.9%), followed by the 6 years old group (9.5%), and significant differences existed between the prevalences of these two groups and that of the adult group (P<0.05). (4) The SCH prevalence was not related with the occurrence of goiter. Conclusion The SCH prevalence is high in Nanchang area and is related to age and sex.