速度向量成像对2型糖尿病患者颈动脉壁的初步研究

目的 应用速度向量成像(VVI)技术评价2型糖尿病患者动脉粥样硬化早期颈动脉弹性改变的临床价值.方法 选取2型糖尿病患者60例作为病例组,并分为A组(32例,无血管并发症)和B组(28例,存在血管并发症).58位健康志愿者作为对照组.分别测量颈动脉管壁6个节段(前外侧壁、前壁、前内侧壁、后内侧壁、后壁、后外侧壁)的速度达峰时间(VTTP)、最大速度(Vmax)、最大应变(Smax)和最大应变率(SRmax).结果 对照组、A组、B组组内各节段间的VTTP、Smax和SRmax的差异无统计学意义(P＞0.05),部分节段间的Vmax差异有统计学意义(P＜0.05),前壁、前外侧壁、后外侧壁高于后壁、后内侧壁、前内侧壁.对照组、A组、B组间对应各节段的VTTP、Vmax、Smax、SRmax差异有统计学意义(P＜0.05).结论 VVI技术能够检测2型糖尿病患者动脉粥样硬化早期颈动脉弹性的改变.

Research on the common carotid artery wall of patients with type 2 diabetic by velocity vector imaging

Objective To assess the elasticity change of common carotid artery in early stage of atherosclerosis in patients with type 2 diabetes by velocity vector imaging(VVI).Methods Sixty patients with type 2 diabetes were divided into group A(32 cases)and group B(28case)according the vascular complications(including Macroangiopathy and Microangiopathy).Patients without vascular complications belong to group A,others belong to group B.Fifty-eight healthy volunteers were supplied as normal control group.Time to the peak of velocity(VTTP),maximum of velocity(Vmax),maximum of strain(Smax),and maximum of strain rate(SRmax)of six segment(anterolateral wall,anterior wall,anteromedial wall,posteromedial wall,posterior wall,posterolateral wall)were measured,which were supplied by VVI automatic analysis software.Results VTTP,Smax and SRmax had no significant differences in any segments intra-group A,B and control group(P＞0.05).Vmax had significant differences in some segments in control group,group A and group B,Vmax of anterior wall,anterolateral wall and posterolateral wall were higher than those of posterior wall,posteromedial wall and anteromedial wall(P＜0.05).VTTP,Vmax,Smax and SRmax of corresponding segments had significant differences among group A,group B and control group(P＜0.05),control group＞group A＞group B(P＜0.05).Conclusions The change of common carotid elasticity can be detected in early stage of atherosclerosis in patients with type 2 diabetes by VVI.