急性心肌梗死患者白细胞计数与心律失常发生率的相关性分析

目的探讨急性心肌梗死(AMI)患者白细胞计数与心律失常发生率的相关性。方法选取2009年4月至2012年5月株洲市恺德心血管病医院收治的203例AMI患者作为研究对象,依据白细胞计数结果将患者分为三组:A组(白细胞计数<8.0×109L-1)45例,B组(白细胞计数8.0×109L-1¹6.0×109L-1)109例,C组(白细胞计数>16.0×109L-1)49例。分析上述三组患者血清心肌肌钙蛋白I(cTnI)、肌酸激酶MB同工酶(CK-MB)的检测结果,以及各组患者心律失常的发生率。结果 C组患者血清cTnI、CK-MB水平显著高于B组(P<0.05),B组患者血清cTnI、CK-MB水平显著高于A组(P<0.05)。C组患者窦性心动过速、心房颤动、室性期前收缩、室性心动过速、心室颤动、房室传导阻滞、束支传导阻滞的发生率显著高于B组(P<0.05),B组患者上述类型心律失常的发生率显著高于A组(P<0.05),且AMI患者白细胞计数与上述类型心律失常的发生率呈正相关(P<0.05)。结论 AMI患者白细胞计数与多数类型心律失常的发生率呈正相关,临床应重视AMI患者白细胞升高的检测。

Analysis on the Correlation between White Blood Count and Incidence Rates of Arrhythmia in Patients with Acute Myocardial Infarction

Objective To explore the correlation between the white blood count （WBC） and incidence rates of arrhythmia in patients with acute myocardial infarction （AMI）. Methods A total of 203 cases of patients with AMI admitted in Kaide Cardiovascular Disease Hospital from Apr. 2009 to May 2012 were selected and divided into 3 groups according to WBC ：45 cases as group A （ WBC 〈 8.0 ×10^9L^-1）, 109 cases as group B（（8.0-16.0） ×10^9L^-1 〈 WBC 〈 16.0 ×10^9L^-1 ） and 49 cases as group C（ WBC 〉 16.0×10^9L^-1） ,respectively. The levels of serum cardiac troponin 1 （cTnl） and creatine kinase MB isoenzyme （ CK-MB）, as well as the incidence rates of arrhythmia of the 3 groups were analyzed retrospectively. Results The levels of serum cTnl and CK-MB of group C were significantly higher than those of group B （P 〈 0.05 ）, and such levels of group B were significantly higher than those of group A （ P 〈 0.05 ）. The incidence rates of sinus tachycardia, atrial fibrillation, premature ventricular beats, ventricular tachycardia, ventricular fibrillation, atrioventrieular block,bundle branch block of group C were significantly higher than those of group B （ P 〈 0.05 ）, and such rates of group B were significantly higher than those of group A （ P 〈 0.05 ）. WBC of AMI patients was positively correlated with the incidence rates of those types of arrhythmia mentioned above （P 〈 0.05）. Conclusion There is a positive correlation between WBC and most types of arrhythmia in patients with AMI, so AMI patients with leukocytnsis should be paid more attention to in clinical practice.