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复发性翼状胬肉切除联合干细胞移植及丝裂霉素C疗效观察
引用本文:关云凤. 复发性翼状胬肉切除联合干细胞移植及丝裂霉素C疗效观察[J]. 国际眼科杂志, 2011, 11(3): 537-538. DOI: 10.3969/j.issn.1672-5123.2011.03.057
作者姓名:关云凤
作者单位:中国陕西省潼关县人民医院眼科,714300
摘    要:目的:观察复发性翼状胬肉根治性切除联合自体角膜缘干细胞移植术中应用丝裂霉素C(MMC)的临床疗效。方法:对98例98眼复发性翼状胬肉行根治性切除,将术眼上方或下方带有角膜缘干细胞的结膜瓣移植于胬肉处的巩膜上,术中联合用0.2g/LMMC治疗。结果:术后反应轻,移植片存活,复发率2%。结论:根治性切除联合角膜缘干细胞移植术中应用MMC治疗复发性翼状胬肉,方法简单,胬肉组织切除彻底,重建了角膜缘的结构和功能,恢复了角膜缘的屏障,复发率低,安全有效,值得推广。

关 键 词:复发性翼状胬肉  根治性切除  角膜缘干细胞  移植  丝裂霉素

Effectiveness of mitomycin C in recurrent pterygium excision combined with corneal limbal stem cell transplantation
Yun-Feng Guan. Effectiveness of mitomycin C in recurrent pterygium excision combined with corneal limbal stem cell transplantation[J]. International Eye Science, 2011, 11(3): 537-538. DOI: 10.3969/j.issn.1672-5123.2011.03.057
Authors:Yun-Feng Guan
Affiliation:Yun-Feng Guan Department of Ophthalmology,the People's Hospital of Tongguan,Tongguan County 714300,Shaanxi Province,China
Abstract:·AIM:To observe the clinical effects of mitomycin C(MMC)on recurrent pterygium excision combined with corneal limbal stem cell transplantation.METHODS:The radical excision of recurrent pterygium was performed in 98 cases 98 eyes.The conjunctival flap with corneal limbal stem cell was transplanted into sclera and 0.2g/L MMC was used during operation.RESULTS:There was slight response after operation and the recurrence rate was 2%.CONCLUSION:The MMC applied in pterygium excision combined with corneal limbal stem cell transplantation is safe and effective.This method can rebuild the structure and function of corneal limbal,it has low recurrent rate and is worthy to be popularized.
Keywords:recurrent pterygium  radical excision  corneal limbal stem cell  transplantation  mitomycin  
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