共聚焦显微镜在真菌性角膜炎中的应用

目的:探讨共聚焦显微镜在真菌性角膜炎中的应用价值。方法:回顾性分析在我院就诊的拟诊为真菌性角膜炎患者42例42眼,行共聚焦显微镜检查,同时行角膜病灶组织刮片染色检查。结果:真菌性角膜炎患者42例42眼,行共聚焦显微镜检查,观察到真菌菌丝为39例39眼,检出阳性率93%(39/42),行角膜病灶组织刮片染色镜检,观察到真菌菌丝为30例30眼,检出阳性率71%(30/42)。统计学分析表明两者差异有统计学意义(χ2=6.574,P<0.05)。结论:共聚焦显微镜是一种无创、高效、直观的检查设备,对真菌性角膜炎的初步诊断有着重要的临床价值。

Application of confocal microscopy in fungal keratitis

AIM:To investigate the application of confocal microscopy in fungal keratitis.METHODS:A total of 42 patients 42 eyes diagnosed with suspected fungal keratitis were performed the confocal microscopy and corneal lesions stained tissue smear examination simultaneously and the results were analysed retrospectively.RESULTS:In 42 patients 42 eyes with fungal keratitis,fungal hyphae was observed in 39 eyes(93%) by the confocal microscopy,however in 30 eyes(71%) by corneal lesions stained tissue smear examination.Statistical analysis showed that the difference was statistically significant(χ 2=6.574,P<0.05).CONCLUSION:Confocal microscopy is a noninvasive,efficient,intuitive inspection equipment,which has important clinical value in the initial diagnosis of fungal keratitis.