虹膜定位联合波前像差引导的Epi-LASIK矫正低中度近视的临床研究

目的:观察虹膜定位联合波前像差引导的Epi-LASIK手术治疗低、中度近视的效果。方法:自愿接受手术的低、中度近视患者100例179眼,将其分为两组,50例90眼接受虹膜定位联合波前引导的Epi-LASIK术(波前组);50例89眼接受常规Epi-LASIK术(常规组);术后随访期间进行裸眼视力(UCVA)、屈光度、像差及高阶像差、视觉质量满意度调查做以研究,并进行相关性分析。结果:术后6mo时,波前组和常规组术后裸眼视力,波前组术前最佳矫正视力(BCVA)与术后裸眼视力,常规组术前最佳矫正视力与术后裸眼视力比较有统计学差异(P<0.05);术后像差较术前均有增加;波前组术后像差、高阶像差较常规组术后像差小,差异有统计学意义(P<0.05);波前组的总体视觉质量满意度比常规组好,有统计学差异(P<0.05)。结论:虹膜定位联合波前引导的Epi-LASIK矫正低、中度近视在有些方面优于常规的Epi-LASIK。

Clinical research on correction of low to moderate myopia by iris location combined with wavefront aberrations guided Epi-LASIK

AIM:To observe the effect of iris location combined with wavefront aberrations guided Epi-LASIK surgery for low to moderate myopia.METHODS:All of 100 patients 179 eyes with low to moderate myopia were randomly divided into two groups,one group of 50 patients 90 eyes received wavefront-guided joint iris location of Epi-LASIK(wavefront group) surgery;the other group of 50 patients 89 eyes received routine Epi-LASIK(control group);postoperative uncorrected visual acuity(UCVA),refraction,aberration,higher order aberrations and the satisfaction of visual quality were analyzed and correlation analysis was carried out during follow-up period.RESULTS:After 6 months,there were statistical differences(P<0.05)between wavefront group and control group patients with UCVA after surgery,preoperative best-corrected visual acuity(BCVA) and postoperative UCVA in wavefront group,preoperative BCVA and postoperative UCVA in control group;postoperative aberrations increased compared with the preoperative aberrations.Postoperative wavefront aberrations and high level aberration of wavefront group were smaller than the control group,the difference was statistically significant(P<0.05);the overall satisfaction of visual quality in wavefront group was better than control group,there were significant differences(P<0.05).CONCLUSION:The iris location combined with wavefront guided Epi-LASIK is better than the conventional Epi-LASIK in some aspects of correction of high myopia.