中心性渗出性脉络膜视网膜病变的吲哚青绿造影特征

目的:分析中心性渗出性脉络膜视网膜病变(central exudative chorioretinopathy,CEC)吲哚青绿血管造影(indocyaninegreen angiography,ICGA)特点。方法:应用海德堡造影系统HRA2对24例24眼CEC患者进行荧光素、吲哚青绿眼底血管造影,并对ICGA与眼底荧光造影(fundus fluorescein angiography,FFA)结果进行对比分析。结果:CEC患者24眼FFA均证实为典型性脉络膜新生血管(choroidal neovascularization,CNV)。ICGA早期,24例CEC可见边界清晰的网状CNV。5例见CNV周围局限性脉络膜血管扩张。ICGA晚期可见CNV处染料渗漏或染色。20眼ICGA早期可见宽窄不一的暗环包绕CNV,4眼未见暗环。ICGA晚期,24眼CNV周围均可见暗环。1例患者光动力(photodynamic therapy,PDT)治疗后2mo,因视力继续下降复查ICGA,可见视网膜脉络膜血管吻合(retinal-choroidal anastomosis,RCA)。结论:由HRA2进行的ICGA对CEC的CNV的结构、边界、局部脉络膜静脉的改变、RCA的显示优于FFA。

Characteristics of indocyanine green angiography in central exudative chorioretinopathy

·AIM:To analyze the characteristics of indocyanine green angiography(ICGA)in central exudative chorioretinopathy(CEC).METHODS:A total of 24 cases(24 eyes)with CEC were examined with fundus fluorescein angiography(FFA)and ICGA using Heidelberg retina angiography 2(HRA2).The images of ICGA and FFA were analyzed.RESULTS:The choroidal neovascularization(CNV)of CEC was classic CNV confirmed by FFA.In early phase of ICGA,24 CEC eyes showed a well-defined CNV and 5 eyes showed local dilatation of choroidal vessels around lesion.In the late phase of ICGA,CNV showed dye leakage or staining.In the early phase of ICGA,20 eyes showed a dark rim around CNV and the other 4 eyes without the dark rim.In the late phase of ICGA,all CEC eyes showed a dark rim around CNV.The repeated ICGA images of a patient with CEC treated by photodynamic therapy(PDT)2 months ago showed retinal-choroidal anastomosis(RCA).CONCLUSION:The structure,border,changes of local choroidal vessels and RCA of CNV were more clearly displayed on ICGA performed by HRA2 than on FFA in patients with CEC.