剥脱综合征并发白内障患者超声乳化术后2a眼压变化及其相关因素的临床研究

目的:研究剥脱综合征并发白内障患者和老年性白内障在超声乳化术后2a内眼压变化情况及相关因素。方法:对49例54眼剥脱综合征并发白内障的患者实施超声乳化人工晶状体植入术,依据眼压情况又分为剥脱综合征并发白内障(XFS)亚组(29例31眼)及剥脱综合征并发白内障和青光眼(XFG)亚组(20例23眼)。同期选择老年性白内障患者134例152眼行超声乳化人工晶状体植入术作为对照依据眼压情况分为白内障亚组(86例93眼)及并发开角青光眼组(POAG)亚组(48例59眼)。两组眼压用药控制正常后手术。比较两组在超声乳化术后2a内眼压的变化。结果:术前剥脱组基础眼压高于对照组(21.85±2.23mmHgvs18.62±3.12mmHg,P=0.002)。在超声乳化术后2a内,两组眼压均降低(17.60±3.23mmHgvs15.08±3.18mmHg,P=0.0037)。统计分析表明与术中灌注量相关。XFG组眼压降低更明显。结论:在超声乳化术后2a内,剥脱综合征组比对照组眼压降低明显。

Study of IOP and correlative factors in exfoliation syndrome combined with cataract 2 years after phacoemulsification

·AIM:To compare the change of intraocular pressure(IOP)and correlative factors in exfoliation syndrome combined with cataract and senile cataract 2 years after phacoemulsification.METHODS:A total of 49 patients 54 eyes with exfoliation syndrome combined with cataract underwent phacoemulsification and intraocular lens(IOL)implantation.Based on IOP,they were divided into exfoliation syndrome combined with cataract(XFS)sub-group(29 cases 31 eyes)and exfoliation syndrome combined with cataract and glaucoma(XFG)sub-group(20 cases 23 eyes).134 senile cataract patients 152 eyes received phacoemulsification and IOL implantation and were selected as a control at the same period;according to IOP,they were divided into cataract group(86 cases 93 eyes)and cataract combined with open angle glaucoma sub-group(48 cases 59 eyes).The exfoliation syndrome combined with cataract group and control group underwent surgery after IOP was normal by medication and the change of IOP was compared within 2 years after phacoemulsification.RESULTS:Preoperative IOP of exfoliation syndrome sub-group was higher than that of the control group(21.85±2.23mmHg vs 18.62±3.12mmHg,P=0.002).Two years after phacoemulsification,IOP lowered in both groups(17.60±3.23mmHg vs 15.08±3.18mmHg,P=0.0037).Statistical analysis showed that it was related with surgical perfusion.IOP of XFG group had significantly decreased.CONCLUSION:The exfoliation syndrome combined with cataract group have significantly lower IOP than the control group 2 years after phacoemulsification.