颅内软骨瘤的CT和MRI表现与病理对照

目的探讨颅内软骨瘤的CT和MRI特征及其病理基础。资料与方法回顾性分析5例经手术病理证实的颅内软骨瘤的影像学表现。5例均行头颅CT、MRI平扫及增强扫描。结果 5例中肿瘤位于颅底者4例,大脑镰区者1例。CT表现为不规则分叶状肿块,边界清楚,密度不均匀,5例伴明显钙化,瘤周无水肿,4例邻近骨质破坏,增强扫描无或轻度强化。MRI上肿块信号不均,实质部分T1Wl呈低或混杂信号,T2WI呈高或高低混杂信号,钙化部分T1Wl及T2WI呈低信号,增强扫描5例均为明显不均匀强化,呈"石榴籽征"。结论颅内软骨瘤的CT、MRI表现具有一定特征性,结合临床,可提高其诊断准确率。

Intracranial Chondroma: Correlation of CT and MRI Findings and Pathology

Objective To investigate the CT,MRI and pathologic features of intracranial chondroma.Materials and Methods The imaging findings of 5 patients with intracranial chondroma confirmed by operation and pathology were analyzed retrospectively.Plain and enhanced CT and MRI scanning were performed in all of the cases.Results Among 5 cases,4 cases were located at skull base,and 1 case was originated from the falx.CT scans usually showed well demarcated,irregular lobulated and variable density masses with obvious calcifi cations(5/5),not or slightly enhancement,without peritumoral edema,often accompanied by erosion and destruction of surrounding bone(4/5).The parenchyma of the tumors appeared as heterogeneous hypointense on T1WI,and hyperintense or mixed hyper and hypo-intense on T2WI,while the calcifi cation in the mass displayed hypointense on T1WI and T2WI.All the cases presented significantly inhomogeneous enhancement on post-contrast MRI,demonstrating typical "pomegranate seed" sign.Conclusion There are some characteristic CT and MRI features in intracranial chondroma,its diagnostic accurate rate can be improved combined with the patient’s clinical information.