序贯性应用肝动脉化疗栓塞与瘤内无水酒精注射治疗巨块型肝癌144例

 目的 观察经皮肝动脉化疗栓塞（TACE）和CT引导下经皮穿刺瘤内无水酒精（PEI）序贯性治疗巨块型原发性肝癌的疗效。方法 144例无远处转移巨块型原发性肝癌先经TACE术治疗，2周后再进行4 ~ 6次PEI治疗。结果 PR 96例（66.7 %），MR 33例（22.9 %），SD 15例（10.4 %），二期可切除69例，手术切除率47.9 %。随访结果显示：6个月、1、2、3年生存率分别为：93.8 %、75.0 %、59.0 %、31.9 %。结论 TACE与PEI序贯性治疗中晚期巨块型肝癌疗效较显著，使原不能手术切除的肝癌可以适应手术治疗，延长了患者的生存期，提高了患者生活质量

The curative effect of TACE combined with PEI sequentially on massive hepatocellular carcinoma for 144 cases

Objective To study the effect of transcatheter arterial chemoembolization (TACE) com－bined with PEI (percutaneous ethylalcohol injection) sequentially on MHCC(massive hepatocellular carcinoma). Methods TACE was performed on 144 patients with MHCC without distant metastasis. After 2 weeks,PEI was done for 4 to 6 times. Results PR, MR and SD were 96 cases(66.7 %), 33 cases (22.9 %) and 15 cases(10.4 %). The rate of resection was 47.9 %. The follow-up results indicated that the survival rates at 6th month, 1st, 2nd and 3rd year after TACE were 93.8 %, 75.0 %, 59.0 % and 31.9 %. Conclusion The effi－cacy of TACE combined with PEI on massive hepatocellular carcinoma sequentially was significant. It made the unresectable hepatocellular carcinoma suitable to be resected. With the therapy, the life of MHCC patients were prolonged, and the quality of life was improved.