Reversible inflammatory and vacuolar myopathy with vitamin E deficiency in celiac disease |
| |
Authors: | Kleopa Kleopas A Kyriacou Kyriacos Zamba-Papanicolaou Eleni Kyriakides Theodoros |
| |
Affiliation: | Department of Clinical Neurosciences, Cyprus Institute of Neurology and Genetics, P.O. Box 23462, Nicosia, Cyprus. |
| |
Abstract: | We report a patient with late-onset celiac disease and neurological manifestations including myopathy, polyneuropathy, and ataxia. Laboratory investigations showed anti-gliadin antibodies and severe vitamin E deficiency. Muscle biopsy revealed inflammatory infiltrates and rimmed vacuoles, similar to those found in inclusion-body myositis. A gluten-free diet and vitamin E supplementation reversed both the clinical neurological manifestations and the abnormalities in the muscle biopsy. Anti-gliadin antibodies were no longer present. This case illustrates the spectrum of neurological complications of celiac disease and documents the occurrence of reversible pathology resembling inclusion-body myopathy in the muscle. |
| |
Keywords: | anti‐gliadin antibodies ataxia gluten enteropathy inclusion‐body myopathy malabsorption neuropathy |
本文献已被 PubMed 等数据库收录! |
|