Characteristics of estradiol receptor system of the anterior hypothalamus and adenohypophysis in guinea pigs

The presence of a specific estradiol-receptor system (E₂-R) with limited capacity and with a high degree of strength of formation of the E₂-R complex was demonstrated in the cytosol of the adenohypophysis, and anterior hypothalamus of guinea pigs in experiments in vivo and in vitro. The physicochemical properties of the E₂-R system of the adenohypophysis and anterior hypothalamus differ in certain parameters. The E₂-R complexes of the cytosols of the adenohypophysis and anterior hypothalamus formed at different temperatures are not identical.Laboratory of Endocrinology, All-Union Research Institute of Obstetrics and Gynecology, Ministry of Health of the USSR, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR L. S. Persianinov.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 85, No. 1, pp. 70–73, January, 1978.