新型甲型H1N1流感危重症临床分析

目的探讨新型甲型H1N1流感危重症患者的临床特点,加深认识,提高诊治水平。方法回顾性分析2009年11月—2011年2月收治的经临床和实验室确诊的8例新型甲型H1N1流感危重病例的临床资料。结果治愈6例,好转1例,死亡1例。结论青壮年、肥胖、伴基础疾病和妊娠的甲型H1N1流感患者易进展为危重症;早期应用奥司他韦,积极治疗基础疾病,控制细菌、真菌感染和液体出入量,实时机械通气并合理应用激素等综合治疗可改善预后,降低病死率。

Clinical Analysis of 8 Critically Ill Patients with New Influenza A(H1N1)Viral Infection

Objective To investigate clinical characteristics of critically ill patients with new influenza A(H1N1) viral infection.Methods The clinical features of 8 critically ill patients with new influenza A(H1N1) viral infection hospitalized at Huangshan people′s Hospital from Nov 2009 to Feb 2011 were retrospectively analyzed.Results 7 cases were cured and improveded,1 case died.Conclusion Critical illness in new influenza A(H1N1)was associated with patients under age 65,with obesity,underlying diseases,and pregnancy.Treatments include Oseltamivir treatments at early stage,machine ventilation as soon as acute respiratory distress is identified,enhancing breath way management,active treatment of complicated diseases,protecting important organs function,controlling fluid intake,preventing and controlling lung secondary bacterial or fungal infection,reasonable glucocorticoid application would probably improve prognosis and reduce mortality.