2002-2007年郑州市人间布鲁杆菌病防治情况调查

目的 了解郑州市布鲁杆菌病(简称布病)流行状况,为制订布病防治对策提供科学依据.方法 2002-2007年,在郑州市选择巩义市为固定监测点,其他县(市、区)作为郑州市非固定监测点,每个县(市、区)选择4或5个乡(镇、场)连续监测,开展监测工作.2002-2005年应用布鲁杆菌素对固定监测点和非固定监测点职业重点人群进行皮内变态反应试验,对有可疑临床表现或皮内变态反应试验阳性人员做试管凝集试验(SAT);2006、2007年在非固定监测点开展家畜饲养繁殖企业做SAT检查.操作方法及判定标准均按<布鲁氏菌病防治手册>进行.结果 2002-2007年巩义市共调查13 831人,做皮内变态反应试验3744人,皮试阳性38人,阳性率1.01%(38/3744):做SAT检查2693人,阳性54人,阳性率2.01%(54/2693).确诊新发病例44例.2002-2005年郑州市11个非固定监测点共做皮内变态反应试验13 136人,皮试阳性82人,阳性率0.62%(82/13 136):2002-2007年做血清学检查1316人,SAT阳性66人,阳性率为5.02%,确诊51例新发病例.其中2006、2007年分别对242、688名饲养繁殖食业人员做SAT检查,阳性17、16人,阳性率分别为7.02%(17/242)、2.33%(16/688).结论 郑州市人间布病疫情有回升趋势,建议政府应加大经费投入,开展布病疫区监测调查和消毒工作,防止疫情扩大蔓延.

Investigation of the prevention and cure of human brucellosis in Zhengzhou from 2002 to 2007

Objective To understand the epidemicological condition of human brucellosis in Zhengzhou city to provide scientific evidence for future preventive and control measures. Methods Surveillance on high risk populations were done in the designated monitoring Gongyi City and other randomized monitoring cities or counties (4 or 5 towns or farms were selected in each city or county) during the year from 2002 to 2007. The intradermic allergy test with brucellin were carried out among high risk populations who had been in close touch of domestic animals or their products in those cities, and standard tube agglutination test(SAT) were used for those who had suspected clinic symptom or positive result of intradermie allergy test during 2002 to 2005. The SAT investigations for enterprises of livestock breeding were performed in non-designated monitoring cities. All manipulation methods and judging standards were according to the manual of prevention and treatment for human brucellosis. Results In the designated monitoring city Gongyi from 2002 to 2007, a total of 13 831 people were investigated, among whom 3744 peoples were tested by intradermic allergy test and the positive rate was 1.01%(38/3744). Fifty-four cases were positive in SAT among 2693, and the positive rate of SAT was 2.01%(54/2693). Forty-four new cases were diagnosed. In the 11 non-designated monitoring city from 2002 to 2005, 13 136 persons were treated by intradermic allergy test, the positive rate was 0.62% (82/13 136), among these 1316 persons were treated by SAT and 66 patients were positive. The positive rate was 5.02% (66/1316) from 2002 to 2007. Fifty one new cases were diagnosed. In the enterprises of domestic animals breeding, among 242 and 688 employees were treated by SAT, 17 and 16 patients were positive, the positive rate were 7.02%(17/242) and 5.02%(16/688) in 2006 and 2007, respectively. Conclusions The infection of human brucellosis in Zhengzhou is rising up. The governments at all levels must put large amounts of funds for the monitoring, investigating and disinfecting to prevent the disease from increasing and outspreading.