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| 新一代风险科学的框架(续完) | |
| 作者姓名： | Daniel Krewski Margit Westphal Gregory M.Paoli Weihsueh A.Chiu Lyle D.Burgoon Ila Cote |
| 摘 要： | 5.2.5 暴露评估 目前,人类暴露评估主要基于人类环境中环境因素的测量水平(美国EPA,2010);某些情况下,内部剂量测量值也可能通过生物监测(Hays 和Aylward,2008)或药代动力学模型(Barton等,2007)获取.在NexGen方法中,暴露评估将更侧重通过先进的生物监测技术(NRC,2012)结合新高通量方法,获得大量环境因素暴露指标(Jones等,2012),从而直接测量人类关键的毒性通路扰动. |
A Framework for the Next Generation of Risk Science |
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| Daniel Krewski,Margit Westphal,Gregory M.Paoli,Weihsueh A.Chiu,Lyle D.Burgoon,Ila Cote.A Framework for the Next Generation of Risk Science[J].Journal of Labour Medicine,2015,32(4). | |
| Institution: | 1. McLaughlin Centre for Population Health Risk Assessment,University of Ottawa, Ottawa, Ontario, Canada;Risk Sciences International, Ottawa, Ontario, Canada 2. McLaughlin Centre for Population Health Risk Assessment,University of Ottawa, Ottawa, Ontario, Canada 3. Institute for Chemical Safety Sciences, The Hamner Institutes for Health Sciences, Research Triangle Park, North Carolina, USA 4. Risk Sciences International, Ottawa, Ontario, Canada 5. National Center for Environmental Assessment, U.S.Environmental Protection Agency, Washington, DC, USA |
| Abstract: | |
| Keywords: | @@ |