西藏高原世居藏族酒精性肝硬化的特点

对91例酒精性肝硬化确诊病例进行统计分析。结果显示，西藏高原世居世藏族酒精性肝硬化占同期住院各种肝硬化42．3％，每日平均饮青梨酒与啤酒量为4601.7ml，饮白酒量为607.8ml。从初次饮酒至初次就诊的平均时间为21．1年。全部病例均有乏力，食欲减退，消化不良与右季肋部隐痛，无肝掌，蜘蛛痣与脾肿大者。肝性脑病的发生率达30．8％，全组96．7％，患者被临床治愈。结果提示，西藏高原地区世居藏族酒精族酒精性肝硬化的发生率显著高于平原地区。平均饮酒量较平均地区者显著为大，发生肝硬化的时间却远较平原地区者长。部分症状的发生率高于文献报道，某些相关体征则缺如。肝性脑病这一严重并发症的发生率高，临床治愈率高。

CLINICAL CHARACTER OF ALCOHOLIC LIVER CIRRHOSIS IN HIGH ALTITUDE NATIVE TIBETANS

To improve the comprehension on the alcoholic liver cirrhosis at high altitude area, 91 cases of high altitude native Tibetans(HANT) with alcoholic liver cirrhosis were analyzed retrospectively. The results showed that among all kinds of liver cirrhosis, the incidence of alcoholic liver cirrhosis in HANT was about 42 3%. The mean quantity of wine drunk by them was 4601 7g qingke wine and beer, together with 607 8g white wine. The time between first drinking wine to first hospital ization was 21 1 years. All the patients had anorexia, dyspepsia and vague pain at right hypochondrium, but no spider angioma and spleen enlargement appeared. The incidence of hepatic encephalopathy was 30 8%. Clinical recovery was achieved in 96 7% the patients. The results suggested that the incidence of alcoholic liver cirrhosis in HANT is significantly higher than that of plain area people. The mean quantity of wine consumed by HANT is significantly larger than that by plain area people, btut their onset time of liver cirrhosis is much longer than that of plain area people. The incidences of some symptoms are higher than reported, and no spider angioma and spleen enlargement could be found. The incidence of hepatic encephalopathy in HANT is high, but its clinical recovery rate is also high.