血清肝功能指标联合检测在鉴别原发性肝癌与肝内胆管癌中的应用

目的:探讨血清丙氨酸氨基转移酶(ALT)、天冬氨酸氨基转移酶(AST)、γ-谷氨酰转肽酶(GGT)、碱性磷酸酶(ALP)、总胆红素(TBIL)检测在鉴别原发性肝癌(HCC)及肝内胆管癌(ICC)中的应用。方法:对98例HCC患者和125例ICC患者血清ALT、AST、GGT、ALP、TBIL的水平进行检测,并对比分析。结果:ICC组患者的ALT、AST、GGT、ALP、TBIL水平均明显高于HCC组(PPPP结论:ALT、AST、GGT、ALP、TBIL在ICC组均有明显升高,对HCC及ICC的鉴别诊断有重要价值。

Combined detection of serum indexes of liver function in the differential diagnosis of primary hepatocellular carcinoma and intrahepatic colangiocarcinoma

Objective:To explore the application of the serum levels of alanine aminotransferase(ALT),aspartate aminotransferase ( AST) ,glutamyl transpeptidase( GGT) ,alkaline phosphatase( ALP) and total bilirubin( TBIL) in the differential diagnosis of primary hepatocellular carcinoma(HCC) and intrahepatic colangiocarcinoma(ICC). Methods:The serum levels of ALT,AST,GGT,ALP and TBIL in 98 patients with HCC and 125 patients with ICC were detected and analyzed. Results:The serum levels of ALT,AST,GGT, ALP and TBIL in ICC group were significantly higher than those in HCC group(P<0. 01). The positive rates of ALT,AST,GGT,ALP and TBIL in ICC group were significantly higher than those in HCC group(P<0. 01). The positive rate of joint detection of 5 indexes in ICC group was significantly higher than that in HCC group(P<0. 01). In ICC group,the GGT level is positive correlation with the increasing of ALT. AST and ALP(P<0. 05),the correlation of GGT with TBIL was not found. Conclusions:The serum levels of ALT, AST,GGT,ALP and TBIL in ICC group increase significantly,which has important value in the differential diagnosis of hepatocellular carcinoma and intrahepatic colangiocarcinoma.