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Bonghan System as Mesenchymal Stem Cell Niches and Pathways of Macrophages in Adipose Tissues
Authors:Byung-Cheon Lee  Kyung-Hee Bae  Gil-Ja Jhon  Kwang-Sup Soh
Affiliation:1. Biomedical Physics Laboratory, Department of Physics and Astronomy, Seoul National University, Seoul, Korea;2. Research Division, Korean Pharmacopuncture Institute, Seoul, Korea;3. Department of Physical Education, University of Incheon, Incheon, Korea;4. Department of Chemistry, Ewha Woman''s University, Seoul, Korea
Abstract:A new technique for visualizing Bonghan ducts (BHDs) and Bonghan corpuscles (BHCs) was developed by using a vivi-staining dye, Trypan blue. The dye stains BHDs and BHCs preferentially to adipocytes so that tracking a BHD and a BHC, even inside adipose tissues, is possible. Concerning the functions of the BHD and the BHC in adipose tissues, we propose conjectures: the Bonghan system may be niches for mesenchymal stem cells, which can differentiate into adipocytes, and pathways for macrophages involved in adipogenesis.
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