妊娠期糖尿病早期筛查与妊娠结局

目的:探讨孕妇妊娠期糖尿病(GDM)的发生率,以及妊娠期有糖尿病相关高危因素者与无高危因素者葡萄糖耐量 试验异常的关系及对胎儿、新生儿的影响。方法:对孕中、晚期孕妇进行口服50 g葡萄糖筛查(50 g GCT),血糖≥7.8 mmol／L者做 正规糖耐量试验(OGTT)以明确诊断,并对诊断妊娠期糖耐量降低(GIGT)及GDM给予早期治疗,观察其妊娠结局。结果:50 g GCT阳性率为10.65％,GIGT及GDM发病率分别为3.80％及3.48％。经早诊断、早治疗的孕妇,妊娠并发症、巨大儿、围产儿窒息、 围产儿死亡率明显降低。结论:对所有孕妇进行早期50 g GCT筛查,并对GIGT、GDM进行早治疗,伴有高危因素的孕妇重点监测, 减少了母儿的病死率。

Clincal Analysis of the Relationship Between Early Screening of Gestational Diabetes Mellitus and Outcomes of Pregnancy

Objective:To investigate the incidence of gestational diabetes mellitus (GDM) in our out -patients, and the effect of abnomal OGTT with or without high risk on fetal and neonatal. Methods: 50 g oral glucose screening test (GST) was administered in pregnant women during the second and last trimesters. Glucose valwe of 7.8 mmol/L or obove in venous serum indicates the need for OGTT. Early treatment was offered to patients with GIGT and GDM. Results:The positive rate of 50 g GCT was 10. 65% and the incidence of GIGT and GDM were 3. 80% and 3. 48% respectively. All kinds of complications were declined because of early diagnosis and treatment. Conclusion: It is important to do 50 g GST and early treatment for GIGT and GDM to decline the maternal and fetal morbidity and mortality.