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铅对心功能影响的研究
引用本文:邹和建 王受益. 铅对心功能影响的研究[J]. 中华劳动卫生职业病杂志, 1994, 12(2): 72-75
作者姓名:邹和建 王受益
作者单位:上海医科大学附属华山医院职业病科,上海医科大学附属华山医院心功能室
摘    要:采用多普勒超声心动图技术对54例铅作业工人及24例非铅作业工人进行了收缩功能、舒张功能测定。结果发现铅作业组每分心搏量和心脏指数明显高于对照组并伴有收缩压增高、左室舒张末期内径增大,认为这是心脏的一种代偿作用。左室舒张功能测定采用二尖瓣流入道血流频谱图分析测定,结果表明,各组舒张期时间参数均无显著差异,但流速指标、面积分数在铅作业组中有较显著改变,E峰下降,A峰升高,E/A比值下降。本文结果提示铅作业工人心脏舒张功能减退,其中以铅中毒组舒张功能减退较为显著。

关 键 词:铅,铅中毒,多普勒超声心动图描记术

EFFECTS OF LEAD ON SYSTOLIC AND DIASTOLIC CARDIAC FUNCTIONS
Zou He-jian,Ding Yue,Huang Kai-lian,et al Dept of Occupational Medicine,Hua Shan Hospital,Shanghai Medical University. EFFECTS OF LEAD ON SYSTOLIC AND DIASTOLIC CARDIAC FUNCTIONS[J]. Chinese journal of industrial hygiene and occupational diseases, 1994, 12(2): 72-75
Authors:Zou He-jian  Ding Yue  Huang Kai-lian  et al Dept of Occupational Medicine  Hua Shan Hospital  Shanghai Medical University
Affiliation:Zou He-jian,Ding Yue,Huang Kai-lian,et al Dept of Occupational Medicine,Hua Shan Hospital,Shanghai Medical University,200040
Abstract:Oth systolic and diastolic cardiac functions were evaluated in 54 lead exposed workers and 24 non-exposed workers by Doppler echocardiography. The results showed that cardiac systolic function was increased in exposedgroups and accompanied by elevation of systolic blood pressure,suggesting a compensatory response to the effect oflead on myocardium. The time-related diastolic parameters in exposed grotips were not different from the control,but blood flow velocity through the mitral valve and Doppler area fractions changed significantly in lead exposedgroups.The decrease of diastolic cardiac function was marked in lead intoxication group.
Keywords:Lead Lead poisoning Doppler echocardiography
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