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低剂量CT引导下经皮氩氦刀微创治疗肺部肿瘤的研究
引用本文:刘育新,刘达信,黄浩枝,许长阳,李广忠,刘镜洪,郭新雄,黄燕,陈维清,罗鹏飞. 低剂量CT引导下经皮氩氦刀微创治疗肺部肿瘤的研究[J]. 现代医院, 2010, 10(7): 13-17. DOI: 10.3969/j.issn.1671-332X.2010.07.006
作者姓名:刘育新  刘达信  黄浩枝  许长阳  李广忠  刘镜洪  郭新雄  黄燕  陈维清  罗鹏飞
作者单位:1. 民航广州医院,广东广州,510406
2. 广州南洋肿瘤医院,广东广州,510406
3. 中山大学公共卫生学院,广东广州,510080
基金项目:广东省医学科研基金立项课题 
摘    要:目的探讨低剂量CT引导下经皮氩氦刀微创治疗肺部肿瘤的可行性。方法采用随机对照试验方法,采用常规剂量引导的对照组与采用低剂量引导的试验组各20例;记录两组间CT引导下氩氦刀冷冻术中的影像学特性、表现与CT引导下辐射剂量的差异性是否有统计学意义。结果两组不同剂量CT引导下肿瘤影像学特性、术中并发症(出血、气胸)图像质量评价影像学表现差异无统计学意义,两组噪声与伪影差异有统计学意义(p<0.05);在15mA引导扫描时候,单次扫描CT剂量加权指数(CTDIvol)从常规的17.95mGy降低至2.26mGy,对照组CT下引导肺部肿瘤扫描的剂量长度乘积(DLP)为(6426.5±4352.21)mGy.cm;试验组DLP为(2492.68±1179.52)mGy.cm;DLP差异有统计学意义[10](p<0.05)。结论低剂量CT引导下经皮氩氦刀微创治疗肺部肿瘤方法,减低患者辐射剂量,可确保手术顺利实施的整个过程,值得同行借鉴与推广。

关 键 词:低剂量CT  冷冻疗法  微创治疗  肺部肿瘤

LOW-DOSE CT-GUIDED PERCUTANEOUS MINIMALLY INVASIVE CRYOSURGICAL TREATMENT OF LUNG TUMORS
Affiliation:LIU Yuxin, LIU Daxin, HUANG Haozhi, et al Hospital of Guangzhou Civil Aviation, Guangdong,510406, PRC
Abstract:Objective To evaluate low dose CT - guided percutaneous cryosurgical the feasibility of mini- really invasive treatment of lung cancer. Methods A randomized controlled trial, the conventional dose used to guide the control group and low dose group to guide the trial of 20 cases ; Recorded between the two groups CT guided cryoa- blatian surgery, imaging features, performance, and CT - guided radiation dose difference is statistically significant. Results The two different doses of CT - guided tumor imaging characteristics, intraoperative complications ( bleed- ing, pneumothorax) Imaging evaluation of image quality showed no significant difference, Noise and artifacts in the two groups was statistically significant difference (p 〈 0. 05 ) ; When the scan 15mA guide, a single dose CT scanning weighted index (CTDIvol) reduced from the conventional 17.95 mGy to 2. 26 mGy, Under the control CT scan guided lung tumor dose length product (DLP) was 6 426. 5 ±4 352. 21 ( mGy. era) ; DLP test group was 2 492.68 ± 179. 52 ( mGy. cm) ; DLP difference was statistically significant(p 〈 0. 05 ). Conclusion Low dose CT guided per- cutaneous cryosurgical method of minimally invasive treatment of lung cancer, reduce the patient radiation dose, will ensure smooth implementation of the entire surgical process, learn from and promote peer - worth.
Keywords:Low- dose CT   Cryotherapy   Minimally invasive treatment   Lung tumor
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