莫西沙星注射液治疗呼吸道细菌性感染的临床研究

目的观察莫西沙星注射液治疗呼吸道细菌性感染的临床疗效与安全性。方法将60例呼吸道细菌性感染患者随机分为治疗组和对照组各30例。治疗组给予莫西沙星注射液静脉滴注;对照组给予左氧氟沙星注射液静脉滴注,疗程均为7～14d。结果治疗组临床总有效率为93.3%,高于对照组的76.7%;细菌清除率为92.0%,高于对照组的80.8%,差异均有统计学意义(P<0.05)。治疗组和对照组不良反应发生率分别为13.3%、16.7%,差异无统计学意义(P>0.05)。结论莫西沙星注射液治疗呼吸道细菌性感染疗效显著,值得临床推广应用。

Clinical study of Moxifloxacin injection in treatment of bacterial infections of respiratory tract

Objective To evaluate the efficacy and safety of moxifloxacin injection in the treatment of respiratory tract bacterial infections.Methods A total of 60 patients were randomly divided into treatment group and control group（30 in each）.The treatment group was treated with moxifloxacin injection,the control group was treated with levofloxacin injection both groups were treated for 7~14d.Results The total clinical effective rate was 93.3%in treatment group and 76.7% in control group（P0.05）.The bacterial eradication rate in treatment group and in control group were 92.0% and 80.8% respectively（P0.05）.There was significant difference between two group in the clinical efficacy.The incidence rate of adverse reactions was 13.3% in the treatment group and 16.7% in the control group（P0.05）.Conclusion Moxifloxacin injection is an effective and safe antibiotics for the treatment of respiratory tract bacterial infections.