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胺碘酮与普罗帕酮治疗阵发性心房颤动的疗效研究
引用本文:茅斌. 胺碘酮与普罗帕酮治疗阵发性心房颤动的疗效研究[J]. 中国实用医药, 2007, 2(26): 22-23
作者姓名:茅斌
作者单位:上海崇明庙镇人民医院,202153
摘    要:目的对比研究静脉推注胺碘酮与普罗帕酮转复阵发性心房颤动的效果。方法122例房颤持续时间<48h的患者随机分为两组,胺碘酮组62例:胺碘酮5mg/kg10min内静脉推注;普罗帕酮组60例:普罗帕酮70mg静脉推注,5~10min注完。观察30min若未转复可重复应用。结果转复率:胺碘酮组69·4%(43/62),普罗帕酮组60%(36/60),两组转复率比较差异无统计学意义(P>0·05)。结论胺碘酮和普罗帕酮对阵发性房颤均有较高的转复率。

关 键 词:阵发性心房颤动  胺碘酮  普罗帕酮

Comparing study on the effects of amiodarone and propafenone in converting paroxysmal atrial fibrillation
MAO Bin. Comparing study on the effects of amiodarone and propafenone in converting paroxysmal atrial fibrillation[J]. China Practical Medical, 2007, 2(26): 22-23
Authors:MAO Bin
Abstract:Objective To compare the effects of intravenous amiodarone and propafenone in converting paroxysmal atrial fibrillation.Methods 122 patients with atrial fibrillation lasting<48 hours were randomly divided into 2 groups:Amiodarone group(n=62) were treated intravenously with 5 mg/kg,amiodarone within 10 min;Propafenone group(n=60) were treated intravenously with 70 mg propafenone within 5-10 min.After 30 minutes,if sinusrhythm was not anverted,the above intravenous injection can be given again.Results The resuscitation rate of two groups was 69.4%(43/62) and 60%(36/60) respectively(P>0.05).Conclusion Both amiodarone and propafenone have a high converting-ratio in treatment of atrial fibrillation.
Keywords:Paroxysmal atrial fibrillation  Amiodarone  Propafenone
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