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| 血管痉挛对蛛网膜下腔出血后脑血管病理性改变的影响 | |
| 引用本文： | 胡立民,胡深,魏学忠.血管痉挛对蛛网膜下腔出血后脑血管病理性改变的影响[J].临床军医杂志,2012,40(3):519-521. |
| 作者姓名： | 胡立民 胡深 魏学忠 |
| 作者单位： | 1. 解放军沈阳军区大连疗养院,辽宁大连,116033 2. 深圳市第六人民医院神经外科,广东 深圳,518052 3. 解放军沈阳军区总医院神经外科,辽宁沈阳,110015 |
| 摘 要： | 目的探讨蛛网膜下腔出血(SAH)性脑血管痉挛(CVS)与血管壁病理学改变之间的因果关系。方法采用药理学预阻滞法,通过光镜和电镜对42只猫SAH后CVS的形成及其对血管壁病理性改变的影响作用进行观察。结果预先使用血管外周阻滞剂可以明显地减轻SAH所致的CVS反应程度,并使血管壁发生的病理性改变也随之减轻。结论 CVS是血管壁发生病理性改变的成因,继而又成为影响SAH预后的主要原因之一。预防或阻止CVS的发生,可有效地防止血管壁发生相应的病理学改变。 |
| 关 键 词： | 猫 蛛网膜下腔出血 脑血管痉挛 罂粟硷 654-Ⅱ 电镜观察 |
Effects of cerebral vasospasm following subarachnoid hemorrhage to cerebrovascular pathological changes |
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| Hu Li-min , Hu Shen , Wei Xue-zhong.Effects of cerebral vasospasm following subarachnoid hemorrhage to cerebrovascular pathological changes[J].Clinical Journal of Medical Officer,2012,40(3):519-521. | |
| Authors: | Hu Li-min Hu Shen Wei Xue-zhong |
| Institution: | 1.Dalian Sanatorium of Shenyang Command,PLA,Dalian Liaoning 116033,China;2.Department of Neurosurgery,Sixth People Hospital of Shenzhen,Shenzhen Guangdong 518052,China;3.Department of Neurosurgery,General Hospital of Shenyang Command,Shenyang Liaoning 110015,China) |
| Abstract: | Objective To evaluate the relation between cerebral vasospasm(CVS) following subarachnoid hemorrhage(SAH) and pathological changes in vessel wall.Methods The emergence and effect of cerebral vasospasm(CVS) following SAH to pathological changes in vessel wall in 42 cats were observed by pharmacological block method with photo-electronic microscopy.Results Prophylactic use of paravasospam antagonist may reduce obviously reacting extent of CVS following SAH and the pathological changes of the wall.Conclusion CVS is one of main causes of the pathological changes that affects prognosis of SAH.Effectively to prevent and block CVS would prevent effectively the pathological changes of the wall. |
| Keywords: | cat subarachnoid hemorrhage cerebral vasospasm papaverine 645-Ⅱ electron microscopic observation |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |