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3种抗菌药治疗老年性肺炎的药物经济学评价
引用本文:常翠,李青,杨宏图,宁德俄,董淳.3种抗菌药治疗老年性肺炎的药物经济学评价[J].药物流行病学杂志,2004,13(6):341-343.
作者姓名:常翠  李青  杨宏图  宁德俄  董淳
作者单位:1. 深圳市人民医院暨南大学第二附属医院药学部,广东深圳,518020
2. 山西医科大学附属医院
摘    要:目的:评价3种抗菌药治疗老年性肺炎的疗效及经济效果。方法:选择372例老年性肺炎患者,随机分为3组,分别给予头孢曲松钠、左氧氟沙星、洛关沙星治疗,观察各组疗效并运用药物经济学方法进行分析。结果:3组治疗有效率分别为80.65%、87.1%、72.58%;不良反应发生率分别为7.65%、6.35%、13.81%。平均成本一效果比分别为6528、10392、11196。结论:药物经济学分析结果为头孢曲松钠优于左氧氟沙星,优于洛关沙星。

关 键 词:抗菌药  老年性肺炎  药物经济学  成本-效果分析
文章编号:1005-0698(2004)06-0341-03

Pharmacoeconomic Evaluation of Three Kinds of Antibacterial in the Treatment of Senile Pneumonia
Chang Cui,Li Qing,Yang Hongtu,Ning Dee,Dong Chun.Pharmacoeconomic Evaluation of Three Kinds of Antibacterial in the Treatment of Senile Pneumonia[J].Chinese Journal of Pharmacoepidemiology,2004,13(6):341-343.
Authors:Chang Cui  Li Qing  Yang Hongtu  Ning Dee  Dong Chun
Institution:Chang Cui,Li Qing,Yang Hongtu,Ning Dee,Dong ChunDepartment of Pharmacy of the People's Hospital of Shenzhen City,The Second Affiliated Hospitalof Jinan University,Shenzhen 518020,P.R.China
Abstract:Objective: To evaluate the therapeutic efficacy and pharmacoeconomic effect of three kinds of anti bacterial in the treatment of senile pneumonia.Method: 372 senile patients with pneumonia were randomly divided into three groups, They were given ceftriaxone,levofloxacin and lomefloxacin respectively. Their therapeutic effects were observed and pharmacoeconomic analysis was made.Result: The effective rates of the three groups were 80.65% , 87.1% and 72.58% ,while the adverse drug reaction rates were 7.65% , 6.35% and 13.81% , the cost effectiveness ratios were 6 528,10 392 and 11 196 respectively.Conclusion: The pharmacoeconomic analysis indicated that ceftriaxone was superior to both levofloxacin and lomefloxacin.
Keywords:Antibacterial  Senile pneumonia  Pharmacoeconomics  Cost  effectiveness analysis
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