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中间锦鸡儿黄酮类成分的研究
引用本文:施蛟,陈博,孙智华,胡昌奇.中间锦鸡儿黄酮类成分的研究[J].药学学报,2003,38(8):599-602.
作者姓名:施蛟  陈博  孙智华  胡昌奇
作者单位:复旦大学,药学院,天然药物化学教研室,上海,200032
基金项目:国家自然科学基金项目 (3 0 0 70 0 85 )
摘    要:目的研究中间锦鸡儿的化学成分。方法用溶剂法、色谱法分离化学成分,用波谱法鉴定其结构。结果从中间锦鸡儿中分离得到10个黄酮类化合物,分别鉴定为5,7,4′-三羟基-3,3′-二甲氧基黄酮(1),3,5,7,8,4′-五羟基-3′-甲氧基黄酮(2),槲皮素(3),柠檬黄酮醇(4),槲皮素-3-甲醚(5),2(S)-7,3′,5′-三羟基二氢黄酮(6),5,7,3′,4′-四羟基-3,8-二甲氧基黄酮(7),紫铆查尔酮(8),甘草素(9)和5,7,4′-三羟基-3,8二甲氧基黄酮(10)。结论化合物6为新化合物,其余皆首次从中间锦鸡儿中分离得到。

关 键 词:豆科  中间锦鸡儿  黄酮  2-(S)-7  3′  5′-三羟基二氢黄酮
收稿时间:2002-11-25

Studies on flavonoid constituents of Caragana intermediia
SHI Jiao,CHEN Bo,SUN Zhi-hua,HU Chang-qi.Studies on flavonoid constituents of Caragana intermediia[J].Acta Pharmaceutica Sinica,2003,38(8):599-602.
Authors:SHI Jiao  CHEN Bo  SUN Zhi-hua  HU Chang-qi
Institution:Department of Chemistry of Natural Product, School of Pharmacy, Fudan University, Shanghai 200032, China.
Abstract:AIM: To study the chemical constituents of Caragana intermedia. METHODS: The compounds were separated by chromatography methods, their structures were identified by spectral analysis. RESULTS: Ten compounds were isolated and identified as 5,7,4'-trihydroxy-3,3'-dimethoxyflavone (1), 3,5,7,8,4'-pentahydroxy-3'-methoxyflavone(2), puercetin(3), limocitrin(4), 5,7,3',4'-tetrahydroxy-3-methoxyflavone(5), 7,3',5'-trihydroxyflavanone(6), 5,7,3',4'-tetrahydroxy-3,8-dimethoxyflavone(7), butein(8), liquiritigenin(9) and 5,7,4'-trihydroxy-3,8-dimethoxyflavone(10). CONCLUSION: Compound 6 is a new compound and the others were obtained from this plant for the first time.
Keywords:Leguminosae  Caragana intermedia  flavonoids
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