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胸腺肽静脉注射治疗慢性肝病临床与免疫学疗效的近期观察
引用本文:郑美贞,张定凤,邹淑碧,赵有蓉,张全海,周亚苏,米桢栋.胸腺肽静脉注射治疗慢性肝病临床与免疫学疗效的近期观察[J].重庆医科大学学报,1986(1).
作者姓名:郑美贞  张定凤  邹淑碧  赵有蓉  张全海  周亚苏  米桢栋
作者单位:重庆医科大学第二医院肝炎研究室 (郑美贞,张定凤,邹淑碧,赵有蓉,张全海,周亚苏),卫生部长春生物制品所(米桢栋)
摘    要:本文报道采用国产胸腺肽治疗24例慢性乙型肝炎患者的结果。剂量为每次6—8mg,每日1次疗程3个月。另设齐墩果酸(对照组)作比较。结果,用药后治疗组SGPT下降的显效率为92%,对照组为41.5%。 对SB下降至正常,二组分别为100%及33%。所以,从临床疗效看治疗组优于对照组,提示胸腺肽是治疗慢性乙型肝炎的一种有前途的药品,它可能通过提高抑制性细胞活性,从而对乙肝自身免疫反应及病情恢复具有重要的作用。

关 键 词:胸腺肽  慢性肝炎

A CLINICAL AND IMMUNOLOGICAL STUDY ON THE THYMOPEPTIDE THERAPY FOR CHRONIC LIVER DISEASE
The second Affiliated Hospital, Zhen Meizhen et al.A CLINICAL AND IMMUNOLOGICAL STUDY ON THE THYMOPEPTIDE THERAPY FOR CHRONIC LIVER DISEASE[J].Journal of Chongqing Medical University,1986(1).
Authors:The second Affiliated Hospital  Zhen Meizhen
Institution:The second Affiliated Hospital; Zhen Meizhen et al
Abstract:Twenty four cases of chronic hepatitis were treated with thymopeptide and compared with 24 controlled cases. The results revealed that in thymopeptide group the effective rate was 83.3%, whereas in the control group the effective rate was only 29.2%(P<0.01) . The number of the patients in both group whose SGPT were returned to normal was different (P<0.05) ; and SB decreased to normal level was 100% and 33% respectively (P<0.05) .The authors believed that the thymopeptide probably increased the activity of the TS cell so that it can improve the course of the disease. Obviously, these results showed that there was a significant difference between the study group anp controlled group. It seems that the thymopeptide may be a more effective drug
Keywords:Thymopetide  Chronic hepatitis
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