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Gene expression analysis for the prediction of recurrence in patients with primary Ta urothelial cell carcinoma |
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| Authors: | Schultz Iman J Wester Kenneth Straatman Huub Kiemeney Lambertus A Babjuk Marko Mares Jaroslav Willems Johannes L Swinkels Dorine W Witjes J Alfred Malmström Per-Uno de Kok Jacques B |
| Institution: | Department of Clinical Chemistry, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. |
| Abstract: | OBJECTIVES: The individual recurrence-free period after primary surgery of patients with Ta urothelial cell carcinoma (UCC) cannot be predicted accurately. This study aims at discriminating between patients with primary Ta UCC and long or short recurrence-free periods. METHODS: We investigated mRNA expression of 23 genes in 44 primary Ta tumours (23 and 21 tumours were from patients with long >or=4 yr] or short |
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