| 比较米安色林与阿米替林治疗抑郁症的疗效 |
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| 引用本文： | 骆菊英,骆红,杜凌阳,虞洪.比较米安色林与阿米替林治疗抑郁症的疗效[J].中国临床药学杂志,2007,16(2):70-73. |
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| 作者姓名： | 骆菊英 骆红 杜凌阳 虞洪 |
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| 作者单位： | 1. 浙江萧山医院,精神科,萧山,311200
2. 浙江萧山医院,妇产科,萧山,311200 |
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| 摘 要： | 目的比较米安色林与阿米替林治疗门诊抑郁症的疗效和不良反应。方法将门诊59例抑郁症患者依就诊顺序分为2组,一组服用米安色林,另一组服用阿米替林,治疗8 wk。在治疗前后用HAMD、HAMA、TESS评定疗效和不良反应。结果米安色林抗抑郁疗效与阿米替林相似,而抗焦虑疗效优于阿米替林,并且米安色林起效更快,不良反应小于阿米替林。结论米安色林抗抑郁、抗焦虑疗效确切,起效快,不良反应小。
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| 关 键 词： | 米安色林 阿米替林 抑郁症 |
| 文章编号： | 1007-4406（2007）02-0070-04 |
| 修稿时间： | 2006-04-17 |
Efficacy of mianserin and amitriptyline in the treatment of patients with depression |
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| LUO Ju-ying,LUO Hong,DU Ling-yang,YU Hong.Efficacy of mianserin and amitriptyline in the treatment of patients with depression[J].Chinese Journal of Clinical Pharmacy,2007,16(2):70-73. |
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| Authors: | LUO Ju-ying LUO Hong DU Ling-yang YU Hong |
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| Institution: | 1 Department of Psychiatry; 2 Department of Gynecology and Obstetrics, Xiaoshan Hospital of Zhejiang Province, Xiaoshan 311200, China |
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| Abstract: | AIM To compare the clinical efficacy and safety of mianserin and amitriptyline in the treatment of patients with depression.METHODS Fifty-nine patients with depression were selected and randomly divided into mianserin and amitriptyline groups.One group took mianserin,another group took amitriptyline.The course of treatment was 8 wk.Before and after the treatment,HAMD,HAMA and TESS were used to evaluate the curative effect and the adverse drug reactions.RESULTS It was found that efficacy of mianserin was similar to amitriptyline but the anti-anxious curative effect surpassed amitriptyline.And the mianserin took effect more quickly,the adverse drug reactions were less than amitriptyline.CONCLUSION The anti-depressive and anti-anxious curative effect of mianserin is accurate and quick,with few adverse drug reactions. |
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| Keywords: | mianserin amitriptyline depression |
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