18F-FDG SPECT/CT显像在食管癌治疗前分期诊断中的应用价值

[目的]探讨氟(18F)-氟代脱氧葡萄糖(18F-FDG)双探头符合线路断层融合显像(SPECT/CT)在食管癌诊断中的价值.[方法]149例临床疑诊食管癌患者行18F-FDG双探头符合线路SPECT检查,诊断结果与病理检查结果对照.[结果]149例原发肿块定性诊断的灵敏度、特异性、准确率分别为98.6％( 139/141)、75.0％( 6/8)、96.6％(139/149);253枚可疑转移淋巴结诊断的灵敏度、特异性、准确率分别为94.4％(201/213)、55.0％ (22/40)、84.2％ (223/253);56例患者的78个远处病灶中,最终67个病灶被确诊为转移,其灵敏度、特异性、准确率分别为97.0％(65/67)、90.9％(10/11)、96.2％(75/78).[结论]18F-FDG双探头符合线路SPECT/CT在食管癌治疗前诊断分期上具有较高的准确率和灵敏度,为食管癌术前较好的无创性检查方法.

Application of 18F-FDG SPECT/CT in the Staging of Esophageal Cancer Before Treatment

[Purpose] To explore the clinical value of 18 F-FDG single-photon emission comptuted tomography/computed tomography（SPECT/CT） in the staging of esophageal cancer.[Method]One hundred forty-nine cases with suspected esophageal cancer underwent 18 F-FDG SPECT/CT,and the results were compared with the pathological findings.[Results] Of all the 149 patients,the sensi-tivity,specificity and accuracy of diagnosis of the primary tumors were 98.6%（139/141）,75.0%（6/8） and 96.6%（139/149） respectively,and those of the 253 suspected metastatic lymph nodes were 94.4%（201/213）,55.0%（22/40） and 84.2%（223/253） respectively.Seventy-eight distant lesions were detected in 56 patients,and finally 67 lesions were diagnosed as metastasis.The sensi-tivity,specificity and accuracy of metastasis were 97.0%（65/67）,90.9%（10/11） and 96.2%（75/78） respectively.[Conclusion] 18 F-FDG SPECT/CT has high accuracy and sensitivity in the stag-ing of esophageal cancer before treatment,and is a useful and noninvasive method.