Single X-ray absorptiometry of the forearm: Precision,correlation, and reference data |
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Authors: | T L Kelly G Crane D T Baran |
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Institution: | (1) Hologic, Inc., 590 Lincoln Street, 02154 Waltham, Massachusetts;(2) Department of Orthopaedics, University of Massachusetts Medical Center, Worcester, Massachusetts |
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Abstract: | The performance of a single X-ray absorptiometry (SXA) device incorporating an X-ray tube as a photon source was evaluated with respect to precision in vivo and in vitro, scan time, image quality, and correlation with an existing dual energy X-ray absorptiometry (DXA) device. SXA precision in vivo, expressed as a coefficient of variation (CV), was 0.66% for bone mineral content (BMC) and 1.05% for bone mineral density (BMD). Precision in vitro, based on 78 BMC measurements of a forearm phantom over 195 days, was 0.53%. Correlation with DXA at the 8 mm distal forearm site was high (r=0.97 for BMC and r=0.96 for BMD). A preliminary SXA reference database composed of 151 healthy Caucasian American women was developed to facilitate the interpretation of patient measurements. SXA scan time was 4 minutes and delivered a radiation exposure of 1.68 mrem. SXA image quality and spatial resolution were superior to SPA and comparable to DXA. |
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Keywords: | Single energy x-ray absorptiometry Dual energy x-ray absorptiometry Bone mineral density Bone mineral content |
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