Durable mechanical circulatory support devices |
| |
Authors: | Patel Chetan B Rogers Joseph G |
| |
Affiliation: | Division of Cardiology, Duke University Medical Center, Durham, NC 27710 Duke Clinical Research Institute, Durham, NC 27710 |
| |
Abstract: | Individuals afflicted with advanced systolic heart failure who have become unresponsive to standard medical and electrical therapies are categorized as having American Heart Association stage D heart failure. The high mortality rates for medically treated stage D heart failure have not improved in the last 10 years, and patients at this advanced stage require either palliative measures or surgical management of heart failure. In recent years, surgically implanted ventricular assist devices (VADs) have become available for long-term use and are now commonly used as a therapy for advanced heart failure. The data generated from this early experience have clearly shown that VADs improve survival and quality of life in patients with advanced heart failure when implanted as a temporary measure or as long-term support. However, with a growing heart failure population, there is much work to be done to continually improve VAD technology, patient selection criteria, and postimplantation management to define the optimal role for assist devices in the management of systolic heart failure. |
| |
Keywords: | AVM, arteriovenous malformation BTT, bridge to transplant DT, destination therapy FDA, Food and Drug Administration HMII, HeartMate II HMW, high molecular weight ICD, implantable cardiodefibrillator INR, international normalized ratio INTERMACS, Interagency Registry for Mechanically Assisted Circulatory Support QOL, quality of life RV, right ventricular UNOS, United Network for Organ Sharing VAD, ventricular assist device VT/VF, ventricular tachycardia/ventricular fibrillation vWF, von Willebrand factor REMATCH, Randomized Evaluation of Mechanical Assistance for the Treatment of Congestive Heart Failure |
本文献已被 ScienceDirect PubMed 等数据库收录! |
|