| 3.0TMR磁敏感加权成像测量帕金森病患者基底节区体积 |
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| 引用本文： | 刘芳,范国光,王慈,徐克,孙文阁.3.0TMR磁敏感加权成像测量帕金森病患者基底节区体积[J].中国医学影像技术,2011,27(3):483-486. |
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| 作者姓名： | 刘芳 范国光 王慈 徐克 孙文阁 |
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| 作者单位： | 中国医科大学附属第一医院放射科,辽宁,沈阳,110001 |
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| 摘 要： | 目的 应用3.0T磁共振SWI分析帕金森病患者基底节区体积的变化,探讨其诊断帕金森病的价值。方法 采用3.0T MRI对40例早期、中晚期帕金森病患者和年龄匹配的20名正常人进行扫描,分别测量尾状核、壳核及苍白球的体积,并与Hoehn & Yahr分级及病程行相关性分析。结果 早期、中晚期帕金森病患者壳核体积较正常人分别下降10.79%(P＜0.05)和22.66%(P＜0.05),中晚期患者较早期患者下降13.31%(P＜0.05)。中晚期患者苍白球体积较正常人下降11.65%(P＜0.05),较早期患者下降8.51%(P＜0.05)。帕金森病患者壳核体积与Hoehn & Yahr分级呈负相关 (r=－0.987, P＜0.001),与病程无相关性。结论 MRI体积测量技术能为帕金森病的辅助诊断提供一定帮助。
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| 关 键 词： | 帕金森病 基底节 磁共振成像 磁敏感加权成像 |
| 收稿时间： | 2010/10/23 0:00:00 |
| 修稿时间： | 2010/11/29 0:00:00 |
Measurement of basal ganglia volume of patients with Parkinson disease using 3.0T MR susceptibility-weighted imaging |
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| LIU Fang,FAN Guo-guang,WANG Ci,XU Ke and SUN Wen-ge.Measurement of basal ganglia volume of patients with Parkinson disease using 3.0T MR susceptibility-weighted imaging[J].Chinese Journal of Medical Imaging Technology,2011,27(3):483-486. |
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| Authors: | LIU Fang FAN Guo-guang WANG Ci XU Ke and SUN Wen-ge |
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| Institution: | Department of Radiology, the First Hospital of China Medical University, Shenyang 110001, China;Department of Radiology, the First Hospital of China Medical University, Shenyang 110001, China;Department of Radiology, the First Hospital of China Medical University, Shenyang 110001, China;Department of Radiology, the First Hospital of China Medical University, Shenyang 110001, China;Department of Radiology, the First Hospital of China Medical University, Shenyang 110001, China |
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| Abstract: | Objective To analyze changes of basal ganglia volume of patients with Parkinson disease(PD) with 3.0T MR SWI.Methods Totally 20 patients with early PD,20 patients with advanced PD and 20 age-matched healthy subjects underwent MRI.The volumes of caudate nucleus,putamen and globus pallidus were measured with SWI.Correlation analysis of basal ganglia volume with Hoehn & Yahr grading and the course of PD was carried out.Results Compared with that of normal volunteers,the volume of putamen in patients with early... |
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| Keywords: | Parkinson disease Basal ganglia Magnetic resonance imaging Susceptibility-weighted imaging |
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